Recombinant Human MMP1 Protein (Phe20-Asn469), N-His tagged

• Cat.No.: MMP1-4561H
• Product Overview: Recombinant human MMP1 (Phe20-Asn469) fused with the N-His tag was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: His
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 54.15 kDa
• Protein Length: Phe20-Asn469
• Purity: >90% as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: 0.01M PBS, pH 7.4, 0.02% NLS
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: MMP1 matrix metallopeptidase 1 (interstitial collagenase) [ Homo sapiens (human) ]
• Official Symbol: MMP1
• Synonyms: MMP1; matrix metallopeptidase 1 (interstitial collagenase); CLG, matrix metalloproteinase 1 (interstitial collagenase); interstitial collagenase; fibroblast collagenase; matrix metalloprotease 1; matrix metalloproteinase 1; CLG; CLGN
• Gene ID: 4312
• mRNA Refseq: NM_001145938
• Protein Refseq: NP_001139410
• MIM: 120353
• UniProt ID: P03956

Reviews

08/26/2021

The manufacturer can offer technical support and expertise to guide researchers through the experimental process.

11/09/2020

The manufacturer can play a vital role in supporting and optimizing the research process.

07/20/2020

This guarantees that the protein is reliable, consistent, and suitable for experiments, reducing variability and enhancing the reproducibility of findings.

Q&As

How does MMP1 relate to wound healing?

MMP1 is involved in the remodeling of tissue during wound healing by facilitating the breakdown of damaged extracellular matrix components.

Are there therapeutic implications of targeting MMP1 in cancer treatment?

Inhibiting MMP1 activity is being explored as a potential therapeutic strategy to impede cancer progression and metastasis.

How does MMP1 contribute to tissue remodeling?

MMP1 plays a key role in tissue remodeling by degrading collagen, a major component of the extracellular matrix, which is essential for processes like wound healing.

In what diseases is MMP1 overexpressed?

MMP1 overexpression is associated with various diseases, including rheumatoid arthritis, atherosclerosis, and certain types of cancer.

Can MMP1 be a biomarker for prognosis in cancer patients?

High MMP1 levels have been correlated with poor prognosis in certain cancer types, making it a potential biomarker for predicting disease outcomes.