Recombinant Human MMP11 Protein, GST-tagged

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Recombinant Human MMP11 Protein, GST-tagged

MMP11 Related Products

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Cat.No. : MMP11-5417H
Product Overview : Human MMP11 full-length ORF (1 a.a. - 488 a.a.) recombinant protein with GST-tag at N-terminal.
Description : Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMPs, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 81 kDa
AA Sequence : MAPAAWLRSAAARAL LPPMLLLLLQPPPLL ARALPPDVHHLHAER RGPQPWHAALPSSPA PAPATQEAPRPASSL RPPRCGVPDPSDGLS ARNRQKRFVLSGGRW EKTDLTYRILRFPWQ LVQEQVRQTMAEALK VWSDVTPLTFTEVHE GRADIMIDFARYWHG DDLPFDGPGGILAHA FFPKTHREGDVHFDY DETWTIGDDQGTDLL QVAAHEFGHVLGLQH TTAAKALMSAFYTFR YPLSLSPDDCRGVQH LYGQPWPTVTSRTPA LGPQAGIDTNEIAPL EPDAPPDACEASFDA VSTIRGELFFFKAGF VWRLRGGQLQPGYPA LASRHWQGLPSPVDA AFEDAQGHIWFFQGA QYWVYDGEKPVLGPA PLTELGLVRFPVHAA LVWGPEKNKIYFFRG RDYWRFHPSTRRVDS PVPRRATDWRGVPSE IDAAFQDADGYAYFL RGRLYWKFDPVKVKA LEGFPRLVGPDFFGC AEPANTFL
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : MMP11 matrix metallopeptidase 11 (stromelysin 3) [ Homo sapiens ]
Official Symbol : MMP11
Synonyms : MMP11; matrix metallopeptidase 11 (stromelysin 3); matrix metalloproteinase 11 (stromelysin 3) , STMY3; stromelysin-3; MMP-11; stromelysin III; ST3; SL-3; STMY3;
Gene ID : 4320
mRNA Refseq : NM_005940
Protein Refseq : NP_005931
MIM : 185261
UniProt ID : P24347

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