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Recombinant Human MNDA Protein, GST-tagged

Cat.No. : MNDA-5446H
Product Overview : Human MNDA full-length ORF ( NP_002423.1, 1 a.a. - 407 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
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Description : The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 72.2 kDa
AA Sequence : MVNEYKKILLLKGFELMDDYHFTSI KSLLAYDLGLTTKMQEEYNRIKITD LMEKKFQGVACLDKLIELAKDMPSL KNLVNNLRKEKSKVAKKIKTQEKAP VKKINQEEVGLAAPAPTARNKLTSE ARGRIPVAQKRKTPNKEKTEAKRNK VSQEQSKPPGPSGASTSAAVDHPPL PQTSSSTPSNTSFTPNQETQAQRQV DARRNVPQNDPVTVVVLKATAPFKY ESPENGKSTMFHATVASKTQYFHVK VFDINLKEKFVRKKVITISDYSECK GVMEIKEASSVSDFNQNFEVPNRII EIANKTPKISQLYKQASGTMVYGLF MLQKKSVHKKNTIYEIQDNTGSMDV VGSGKWHNIKCEKGDKLRLFCLQLR TVDRKLKLVCGSHSFIKVIKAKKNK EGPMNVN
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : MNDA myeloid cell nuclear differentiation antigen [ Homo sapiens ]
Official Symbol : MNDA
Synonyms : MNDA; myeloid cell nuclear differentiation antigen; PYHIN3;
Gene ID : 4332
mRNA Refseq : NM_002432
Protein Refseq : NP_002423
MIM : 159553
UniProt ID : P41218

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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