Recombinant Human MNT Protein, GST-tagged

• Cat.No.: MNT-5449H
• Product Overview: Human MNT full-length ORF (BAF84285.1, 1 a.a. - 582 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 88.7 kDa
• AA Sequence: MSIETLLEAARFLEWQAQQQQRARE EQERLRLEQEREQEQKKANSLARLA HTLPVEEPRMEAPPLPLSPPAPPPA PPPPLATPAPLTVIPIPVVTNSPQP LPPPPPLPAAAQPLPLAPRQPALVG APGLSIKEPAPLPSRPQVPTPAPLL PDSKATIPPNGSPKPLQPLPTPVLT IAPHPGVQPQLAPQQPPPPTLGTLK LAPAEEVKSSEQKKRPGGIGTREVH NKLEKNRRAHLKECFETLKRNIPNV DDKKTSNLSVLRTALRYIQSLKRKE KEYEHEMERLAREKIATQQRLAELK HELSQWMDVLEIDRVLRQTGQPEDD QASTSTASEGEDNIDEDMEEDRAGL GPPKLSHRPQPELLKSTLPPPSTTP APLPPHPHPHPHSVALPPAHLPVQQ QQPQQKTPLPAPPPPPAAPAQTLVP APAHLVATAGGGSTVIAHTATTHAS VIQTVNHVLQGPGGKHIAHIAPSAP SPAVQLAPATPPIGHITVHPATLNH VAHLGSQLPLYPQPVAVSHIAHTLS HQQVNGTAGLGPPATVMAKPAVGAQ VVHHPQLVGQTVLNPVTMVTMPSFP VSTLKLA
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: MNT MAX binding protein [ Homo sapiens ]
• Official Symbol: MNT
• Synonyms: MNT; MAX binding protein; max-binding protein MNT; bHLHd3; MAD6; Max interacting protein; MXD6; myc antagonist; ROX; myc antagonist MNT; Max-interacting protein; class D basic helix-loop-helix protein 3
• Gene ID: 4335
• mRNA Refseq: NM_020310
• Protein Refseq: NP_064706
• MIM: 603039
• UniProt ID: Q99583