Recombinant Human MOG Protein, GST-tagged
Cat.No. : | MOG-5466H |
Product Overview : | Human MOG full-length ORF ( AAH35938, 1 a.a. - 295 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 58.19 kDa |
AA Sequence : | MASLSRPSLPSCLCSFLLLLLLQVS SSYAGQFRVIGPRHPIRALVGDEVE LPCRISPGKNATGMEVGWYRPPFSR VVHLYRNGKDQDGDQAPEYRGRTEL LKDAIGEGKVTLRIRNVRFSDEGGF TCFFRDHSYQEEAAMELKVEDPFYW VSPGVLVLLAVLPVLLLQITVGLVF LCLQYRLRGKLRAEIENLHRTFDPH FLRVPCWKITLFVIVPVLGPLVALI ICYNWLHRRLAGQFLEELRKFSSLC YKQRIKSQERETEATRGRGGLLRDH IPRGKEELESLGGGKTPPGR |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | MOG myelin oligodendrocyte glycoprotein [ Homo sapiens ] |
Official Symbol : | MOG |
Synonyms : | MOG; myelin oligodendrocyte glycoprotein; myelin-oligodendrocyte glycoprotein; MOG Ig-AluB; MOG alpha-5; MOGIG2; NRCLP7; MGC26137; |
Gene ID : | 4340 |
mRNA Refseq : | NM_001008228 |
Protein Refseq : | NP_001008229 |
MIM : | 159465 |
UniProt ID : | Q16653 |
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◆ Native Protein | ||
MOG-20 | Native Mouse/Rat MOG (35-55) Protein | +Inquiry |
◆ Lysates | ||
MOG-1126HCL | Recombinant Human MOG cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewExcellent in protein studies.
Reliable, efficient, and effective.
Worked well, great quality.
Q&As (7)
Ask a questionMOG is predominantly expressed on the outer surface of the myelin sheath in the central nervous system.
MOG is a target in autoimmune demyelinating diseases, where the immune system mistakenly attacks it, damaging the myelin sheath.
MOG antibody testing helps diagnose and distinguish different demyelinating diseases, and therapies aim to modulate the immune response to prevent MOG attack.
There are no widely recognized genetic mutations in MOG associated with neurological conditions, but research is ongoing.
MOG contributes to myelin integrity, aiding in proper nerve signal transmission.
MOG antibodies are found in a subset of MS patients, but their exact role in MS pathogenesis is still under investigation.
MOG is involved in the maintenance and stability of the myelin sheath in the central nervous system.
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