Recombinant Human MPZL1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: MPZL1-2360H
• Product Overview: MPZL1 MS Standard C13 and N15-labeled recombinant protein (NP_003944) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 29.1 kDa
• AA Sequence: MAASAGAGAVIAAPDSRRWLWSVLA AALGLLTAGVSALEVYTPKEIFVAN GTQGKLTCKFKSTSTTGGLTSVSWS FQPEGADTTVSFFHYSQGQVYLGNY PPFKDRISWAGDLDKKDASINIENM QFIHNGTYICDVKNPPDIVVQPGHI RLYVVEKENLPVFPVWVVVGIVTAV VLGLTLLISMILAVLYRRKNSKRDY TGCSTSESLSPVKQAPRKSPSDTEG LVKSLPSGSHQGPVIYAQLDHSGGH HSDKINKSESVVYADIRKNTRTRPL EQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: MPZL1 myelin protein zero-like 1 [ Homo sapiens (human) ]
• Official Symbol: MPZL1
• Synonyms: MPZL1; myelin protein zero-like 1; myelin protein zero-like protein 1; FLJ21047; PZR; protein zero related; protein zero-related; immunoglobulin family transmembrane protein; PZRa; PZRb; PZR1b; MPZL1b
• Gene ID: 9019
• mRNA Refseq: NM_003953
• Protein Refseq: NP_003944
• MIM: 604376
• UniProt ID: O95297