Recombinant Human MRI1 Protein, GST-tagged

• Cat.No.: MRI1-4326H
• Product Overview: Human MGC3207 full-length ORF ( AAH01703, 1 a.a. - 369 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This enzyme functions in the methionine salvage pathway by catalyzing the interconversion of methylthioribose-1-phosphate and methythioribulose-1-phosphate. Elevated expression of the encoded protein is associated with metastatic melanoma and this protein promotes melanoma cell invasion independent of its enzymatic activity. Mutations in this gene may be associated with vanishing white matter disease (VMWD). [provided by RefSeq, Jul 2016]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 66.33 kDa
• AA Sequence: MTLEAIRYSRGSLQILDQLLLPKQS RYEAVGSVHQAWEAIRAMKVRGAPA IALVGCLSLAVELQAGAGGPGLAAL VAFVRDKLSFLVTARPTAVNMARAA RDLADVAAREAEREGATEEAVRERV ICCTEDMLEKDLRDNRSIGDLGARH LLERVAPSGGKVTVLTHCNTGALAT AGYGTALGVIRSLHSLGRLEHAFCT ETRPYNQGARLTAFELVYEQIPATL ITDSMVAAAMAHRGVSAVVVGADRV VANGDTANKVGTYQLAIVAKHHGIP FYVAAPSSSCDLRLETGKEIIIEER PGQELTDVNGVRIAAPGIGVWNPAF DVTPHDLITGGIITELGVFAPEELR TALTTTISSRDGTLDGPQM
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: MRI1 methylthioribose-1-phosphate isomerase 1 [ Homo sapiens (human) ]
• Official Symbol: MRI1
• Synonyms: MRI1; methylthioribose-1-phosphate isomerase 1; M1Pi; MRDI; MTNA; Ypr118w; methylthioribose-1-phosphate isomerase; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase 1; mediator of RhoA-dependent invasion; methylthioribose-1-phosphate isomerase homolog; translation initiation factor eIF-2B subunit alpha/beta/delta-like protein; EC 5.3.1.23
• Gene ID: 84245
• mRNA Refseq: NM_001031727
• Protein Refseq: NP_001026897
• MIM: 615105
• UniProt ID: Q9BV20