Recombinant Human MRVI1 Protein
Cat.No. : | MRVI1-5631H |
Product Overview : | Human MRVI1 full-length ORF (ADR83074.1) recombinant protein without tag. |
- Specification
- Gene Information
- Related Products
Description : | This gene is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV). The encoded protein, which is found in the membrane of the endoplasmic reticulum, is similar to Jaw1, a lymphoid-restricted protein whose expression is downregulated during lymphoid differentiation. Studies in mouse suggest that MRV integration at Mrvi1 induces myeloid leukemia by altering the expression of a gene important for myeloid cell growth and/or differentiation, and thus this gene may function as a myeloid leukemia tumor suppressor gene. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, few of which initiate translation at a non-AUG (CUG) start site. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Form : | Liquid |
Molecular Mass : | 65.7 kDa |
AA Sequence : | MALNSPQPGPVESELGKQLLKTGWE GSPLPRSPTQDAAGVGPPASQGRGP AGEPMGPEAGSKAELPPTVSRPPLL RGLSWDSGPEEPGPRLQKVLAKLPL AEEEKRFAGKAGGKLAKAPGLKDFQ IQVQPVRMQKLTKLREEHILMRNQN LVGLKLPDLSEAAEQEKGLPSELSP AIEEEESKSGLDVMPNISDVLLRKL RVHRSLPGSAPPLTEKEVENVFVQL SLAFRNDSYTLESRINQAERERNLT EENTEKELENFKASITSSASLWHHC EHRETYQKLLEDIAVLHRLAARLSS RAEVVGAVRQEKRMSKATEVMMQYV ENLKRTYEKDHAELMEFKKLANQNS SRSCGPSEDGVPRTARSMSLTLGKN MPRRRVSVAVVPKFNALNLPGQTPS SSSIPSLPALSESPNGKGSLPVTSA LPALLENGKTNGDPDCEASAPALTL SCLEELSQETKARMEEEAYSKGFQE GLKKTKELQDLKEEEEEQKSESPEE PEEVEETEEEEKGPRSSKLEELVHF LQVMYPKLCQHWQVIWMMAAVMLVL TVVLGLYNSYNSCAEQADGPLGRST CSAAQRDSWWSSGLQHEQPTEQ |
Applications : | Antibody Production Functional Study Compound Screening |
Usage : | Heating may cause protein aggregation. Please do not heat this product before electrophoresis. |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 25 mM Tris-HCl of pH8.0 containing 2% glycerol. |
Gene Name : | MRVI1 murine retrovirus integration site 1 homolog [ Homo sapiens ] |
Official Symbol : | MRVI1 |
Synonyms : | MRVI1; murine retrovirus integration site 1 homolog; protein MRVI1; inositol 1; 4; 5 triphosphate associated cGMP kinase substrate; IP3R associated cGMP kinase substrate; IRAG; JAW1L; JAW1-related protein MRVI1; IP3R-associated cGMP kinase substrate; inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate; inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate; |
Gene ID : | 10335 |
mRNA Refseq : | NM_001098579 |
Protein Refseq : | NP_001092049 |
MIM : | 604673 |
UniProt ID : | Q9Y6F6 |
Products Types
◆ Recombinant Protein | ||
MRVI1-1939H | Recombinant Human MRVI1 Protein, MYC/DDK-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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