Recombinant Human MSL3 Protein, GST-tagged

• Cat.No.: MSL3-5657H
• Product Overview: Human MSL3L1 full-length ORF ( AAH31210.1, 1 a.a. - 521 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a nuclear protein and has similarity to drosophila male-specific lethal-3 gene. The drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus this encoded protein is thought to play a similar function in chromatin remodeling and transcriptional regulation. This gene has been found to undergo X inactivation. There are four alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 86.2 kDa
• AA Sequence: MSASEGMKFKFHSGEKVLCFEPDPT KARVLYDAKIVDVIVGKDEKGRKIP EYLIHFNGWNRSWDRWAAEDHVLRD TDENRRLQRKLARKAVARLRSTGRK KKRCRLPGVDSVLKGLPTEEKDEND ENSLSSSSDCSENKDEEISEESDIE EKTEVKEEPELQTRREMEERTITIE IPEVLKKQLEDDCYYINRRKRLVKL PCQTNIITILESYVKHFAINAAFSA NERPRHHHVMPHANMNVHYIPAEKN VDLCKEMVDGLRITFDYTLPLVLLY PYEQAQYKKVTSSKFFLPIKESATS TNRSQEELSPSPPLLNPSTPQSTES QPTTGEPATPKRRKAEPEALQSLRR STRHSANCDRLSESSASPQPKRRQQ DTSASMPKLFLHLEKKTPVHSRSSS PIPLTPSKEGSAVFAGFEGRRTNEI NEVLSWKLVPDNYPPGDQPPPPSYI YGAQHLLRLFVKLPEILGKMSFSEK NLKALLKHFDLFLRFLAEYHDDFFP ESAYVAACEAHYSTKNPRAIY
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: MSL3 male-specific lethal 3 homolog (Drosophila) [ Homo sapiens ]
• Official Symbol: MSL3
• Synonyms: MSL3; male-specific lethal 3 homolog (Drosophila); male specific lethal 3 like 1 (Drosophila) , male specific lethal 3 (Drosophila) like 1 , MSL3L1; male-specific lethal 3 homolog; MSL3-like 1; male-specific lethal-3 protein-like 1; MSL3L1; DKFZp586J1822
• Gene ID: 10943
• mRNA Refseq: NM_001193270
• Protein Refseq: NP_001180199
• MIM: 300609
• UniProt ID: Q8N5Y2