Recombinant Human MSR1 Protein, GST-tagged
Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.
Cat.No. : | MSR1-5664H |
Product Overview : | Human MSR1 partial ORF ( NP_619729, 121 a.a. - 220 a.a.) recombinant protein with GST-tag at N-terminal. |
Description : | This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimers disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 36.74 kDa |
AA Sequence : | MEKRIQHILD MEANLMDTEH FQNFSMTTDQ RFNDILLQLS TLFSSVQGHG NAIDEISKSL ISLNTTLLDL QLNIENLNGK IQENTFKQQE EISKLKERVY |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Quality Control Testing: : |
![]() 12.5% SDS-PAGE Stained with Coomassie Blue. |
Gene Name : | MSR1 macrophage scavenger receptor 1 [ Homo sapiens ] |
Official Symbol : | MSR1 |
Synonyms : | MSR1; macrophage scavenger receptor 1; macrophage scavenger receptor types I and II; CD204; SCARA1; scavenger receptor class A member 1; scavenger receptor class A, member 1; macrophage scavenger receptor type III; macrophage acetylated LDL receptor I and II; SRA; SR-A; phSR1; phSR2; |
Gene ID : | 4481 |
mRNA Refseq : | NM_138716 |
Protein Refseq : | NP_619730 |
MIM : | 153622 |
UniProt ID : | P21757 |
◆ Recombinant Protein
MSR1-2026H | Recombinant Human MSR1 Protein, His-tagged | +Inquiry |
MSR1-2090H | Recombinant Human MSR1 Protein, MYC/DDK-tagged | +Inquiry |
Msr1-4195M | Recombinant Mouse Msr1 Protein, Myc/DDK-tagged | +Inquiry |
MSR1-01H | Recombinant Human MSR1 Protein, Fc-tagged | +Inquiry |
MSR1-53H | Recombinant Human MSR1 protein, His-tagged | +Inquiry |
|
◆ Lysates
MSR1-2844HCL | Recombinant Human MSR1 cell lysate | +Inquiry |
MSR1-2288MCL | Recombinant Mouse MSR1 cell lysate | +Inquiry |
MSR1-800RCL | Recombinant Rat MSR1 cell lysate | +Inquiry |
|
Easy access to products and services you need from our library via powerful searching tools.
Copyright © 2007 – 2021 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy