Recombinant Human MTARC1 Protein, Myc/DDK-tagged
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Cat.No. : | MTARC1-01H |
Product Overview : | Recombinant human MTARC1 protein with a C-terminal Myc/DDK-tag was expressed in HEK293T. |
Description : | Catalyzes the reduction of N-oxygenated molecules, acting as a counterpart of cytochrome P450 and flavin-containing monooxygenases in metabolic cycles. As a component of prodrug-converting system, reduces a multitude of N-hydroxylated prodrugs particularly amidoximes, leading to increased drug bioavailability. May be involved in mitochondrial N(omega)-hydroxy-L-arginine (NOHA) reduction, regulating endogenous nitric oxide levels and biosynthesis. Postulated to cleave the N-OH bond of N-hydroxylated substrates in concert with electron transfer from NADH to cytochrome b5 reductase then to cytochrome b5, the ultimate electron donor that primes the active site for substrate reduction. |
Source : | HEK293T |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 37.3 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles |
Storage : | Store it at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris. HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Coomassie blue staining of purified MARC1 protein : |
![]() The protein was produced from HEK293T cells transfected with MARC1 cDNA clone using MegaTran 2.0. |
Gene Name : | MTARC1 mitochondrial amidoxime reducing component 1 [ Homo sapiens (human) ] |
Official Symbol : | MTARC1 |
Synonyms : | MTARC1; mitochondrial amidoxime reducing component 1; MARC1; MOSC1; mitochondrial amidoxime-reducing component 1; MOCO sulphurase C-terminal domain containing 1; MOSC domain-containing protein 1, mitochondrial; moco sulfurase C-terminal domain-containing protein 1; molybdenum cofactor sulfurase C-terminal domain-containing protein 1 |
Gene ID : | 64757 |
mRNA Refseq : | NM_022746 |
Protein Refseq : | NP_073583 |
MIM : | 614126 |
UniProt ID : | Q5VT66 |
◆ Recombinant Protein
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