Recombinant Human MTARC1 Protein, Myc/DDK-tagged MTARC1-01H

Specification Gene Information Related Products

Cat.No. :	MTARC1-01H
Product Overview :	Recombinant human MTARC1 protein with a C-terminal Myc/DDK-tag was expressed in HEK293T.
Description :	Catalyzes the reduction of N-oxygenated molecules, acting as a counterpart of cytochrome P450 and flavin-containing monooxygenases in metabolic cycles. As a component of prodrug-converting system, reduces a multitude of N-hydroxylated prodrugs particularly amidoximes, leading to increased drug bioavailability. May be involved in mitochondrial N(omega)-hydroxy-L-arginine (NOHA) reduction, regulating endogenous nitric oxide levels and biosynthesis. Postulated to cleave the N-OH bond of N-hydroxylated substrates in concert with electron transfer from NADH to cytochrome b5 reductase then to cytochrome b5, the ultimate electron donor that primes the active site for substrate reduction.
Source :	HEK293T
Species :	Human
Tag :	Myc/DDK
Molecular Mass :	37.3 kDa
Purity :	> 80% as determined by SDS-PAGE and Coomassie blue staining
Stability :	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles
Storage :	Store it at -80 centigrade.
Concentration :	>50 ug/mL as determined by microplate BCA method
Storage Buffer :	25 mM Tris. HCl, pH 7.3, 100 mM glycine, 10% glycerol
Coomassie blue staining of purified MARC1 protein :	The protein was produced from HEK293T cells transfected with MARC1 cDNA clone using MegaTran 2.0.

Gene Name :	MTARC1 mitochondrial amidoxime reducing component 1 [ Homo sapiens (human) ]
Official Symbol :	MTARC1
Synonyms :	MTARC1; mitochondrial amidoxime reducing component 1; MARC1; MOSC1; mitochondrial amidoxime-reducing component 1; MOCO sulphurase C-terminal domain containing 1; MOSC domain-containing protein 1, mitochondrial; moco sulfurase C-terminal domain-containing protein 1; molybdenum cofactor sulfurase C-terminal domain-containing protein 1
Gene ID :	64757
mRNA Refseq :	NM_022746
Protein Refseq :	NP_073583
MIM :	614126
UniProt ID :	Q5VT66