Recombinant Human MTARC1 Protein, Myc/DDK-tagged

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Recombinant Human MTARC1 Protein, Myc/DDK-tagged

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Cat.No. : MTARC1-01H
Product Overview : Recombinant human MTARC1 protein with a C-terminal Myc/DDK-tag was expressed in HEK293T.
Description : Catalyzes the reduction of N-oxygenated molecules, acting as a counterpart of cytochrome P450 and flavin-containing monooxygenases in metabolic cycles. As a component of prodrug-converting system, reduces a multitude of N-hydroxylated prodrugs particularly amidoximes, leading to increased drug bioavailability. May be involved in mitochondrial N(omega)-hydroxy-L-arginine (NOHA) reduction, regulating endogenous nitric oxide levels and biosynthesis. Postulated to cleave the N-OH bond of N-hydroxylated substrates in concert with electron transfer from NADH to cytochrome b5 reductase then to cytochrome b5, the ultimate electron donor that primes the active site for substrate reduction.
Source : HEK293T
Species : Human
Tag : Myc/DDK
Molecular Mass : 37.3 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles
Storage : Store it at -80 centigrade.
Concentration : >50 ug/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris. HCl, pH 7.3, 100 mM glycine, 10% glycerol
Coomassie blue staining of purified MARC1 protein :

The protein was produced from HEK293T cells transfected with MARC1 cDNA clone using MegaTran 2.0.

Gene Name : MTARC1 mitochondrial amidoxime reducing component 1 [ Homo sapiens (human) ]
Official Symbol : MTARC1
Synonyms : MTARC1; mitochondrial amidoxime reducing component 1; MARC1; MOSC1; mitochondrial amidoxime-reducing component 1; MOCO sulphurase C-terminal domain containing 1; MOSC domain-containing protein 1, mitochondrial; moco sulfurase C-terminal domain-containing protein 1; molybdenum cofactor sulfurase C-terminal domain-containing protein 1
Gene ID : 64757
mRNA Refseq : NM_022746
Protein Refseq : NP_073583
MIM : 614126
UniProt ID : Q5VT66

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