Recombinant Human MTHFD2L Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: MTHFD2L-6710H
• Product Overview: MTHFD2L MS Standard C13 and N15-labeled recombinant protein (NP_001138450) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: MTHFD2L (Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 2 Like) is a Protein Coding gene. Diseases associated with MTHFD2L include Cutis Laxa, Autosomal Dominant 3 and Cutis Laxa, Autosomal Dominant 1. Among its related pathways are One carbon pool by folate and Metabolism of water-soluble vitamins and cofactors. Gene Ontology (GO) annotations related to this gene include formate-tetrahydrofolate ligase activity and methylenetetrahydrofolate dehydrogenase (NADP+) activity. An important paralog of this gene is MTHFD2.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 37.1 kDa
• AA Sequence: MTVPVRGFSLLRGRLGRAPALGRST APSVRAPGEPGSAFRGFRSSGVRHE AIIISGTEMAKHIQKEIQRGVESWV SLGNRRPHLSIILVGDNPASHTYVR NKIRAASAVGICSELILKPKDVSQE ELLDVTDQLNMDPRVSGILVQLPLP DHVDERTICNGIAPEKDVDGFHIIN IGRLCLDQHSLIPATASAVWEIIKR TGIQTFGKNVVVAGRSKNVGMPIAM LLHTDGEHERPGGDATVTIAHRYTP KEQLKIHTQLADIIIVAAGIPKLIT SDMVKEGAAVIDVGINYVHDPVTGK TKLVGDVDFEAVKKKAGFITPVPGG VGPMTVAMLLKNTLLAAKKIIYTRT RPLEQKLISEEDLAANDILDYKDDD DKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like [ Homo sapiens (human) ]
• Official Symbol: MTHFD2L
• Synonyms: MTHFD2L; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like; probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2; MGC72244; MTHFD2-like; NADP-dependent methylenetetrahydrofolate dehydrogenase 2-like protein; FLJ13105; MGC45532
• Gene ID: 441024
• mRNA Refseq: NM_001144978
• Protein Refseq: NP_001138450
• MIM: 614047
• UniProt ID: Q9H903