Recombinant Human MTMR14 Protein, GST-tagged

• Cat.No.: MTMR14-4274H
• Product Overview: Human FLJ22405 full-length ORF ( AAH01674, 1 a.a. - 417 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a myotubularin-related protein. The encoded protein is a phosphoinositide phosphatase that specifically dephosphorylates phosphatidylinositol 3,5-biphosphate and phosphatidylinositol 3-phosphate. Mutations in this gene are correlated with autosomal dominant centronuclear myopathy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 18.[provided by RefSeq, Apr 2010]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 71.61 kDa
• AA Sequence: MARCRGRFVCPVILFKGKHICRSAT LAGWGELYGRSGYNYFFSGGADDAW ADVEDVTEEDCALRSGDTHLFDKVR GYDIKLLRYLSVKYICDLMVENKKV KFGMNVTSSEKVDKAQRYADFTLLS IPYPGCEFFKEYKDRDYMAEGLIFN WKQDYVDAPLSIPDFLTHSLNIDWS QYQCWDLVQQTQNYLKLLLSLVNSD DDSGLLVHCISGWDRTPLFISLLRL SLWADGLIHTSLKPTEILYLTVAYD WFLFGHMLVDRLSKGEEIFFFCFNF LKHITSEEFSALKTQRRKSLPARDG GFTLEDICMLRRKDRGSTTSLGSDF SLVMESSPGATGSFTYEAVELVPAG APTQAAWLAALSDRETRLQEVRSAF LAAYSSTVGLRAVAPSPSGAIGGLL EQFARGVGLRSISSNAL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: MTMR14 myotubularin related protein 14 [ Homo sapiens ]
• Official Symbol: MTMR14
• Synonyms: MTMR14; myotubularin related protein 14; C3orf29, chromosome 3 open reading frame 29; myotubularin-related protein 14; egg derived tyrosine phosphatase homolog (Drosophila); FLJ22405; FLJ90311; hEDTP; hJumpy; jumpy; NS5ATP4ABP1; egg-derived tyrosine phosphatase homolog; HCV NS5A-transactivated protein 4 splice variant A-binding protein 1; C3orf29; FLJ11546; FLJ46453
• Gene ID: 64419
• mRNA Refseq: NM_001077525
• Protein Refseq: NP_001070993
• MIM: 611089
• UniProt ID: Q8NCE2