Recombinant Human MUC21 Protein, His-tagged

• Cat.No.: MUC21-2462H
• Product Overview: Recombinant Human MUC21 Protein (Ser505-Pro566) with a N-His tag was expressed in E. coli.

Specification

• Description: This gene encodes a large membrane-bound glycoprotein which is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. The encoded protein contains an N-terminal signal sequence, an extracellular mucin domain, a stem domain, a transmembrane domain, and a C-terminal cytoplasmic tail domain. The mucin domain contains O-glycosylation sites and is polymorphic with isoforms containing a variable number of nonidentical proline-, threonine-, and serine-rich tandem repeats of 15 amino acids each. The aberrent expression of this gene is associated with lung adenocarcinoma.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 10.6 kDa
• Protein length: Ser505-Pro566
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 97%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: MUC21 mucin 21, cell surface associated [ Homo sapiens (human) ]
• Official Symbol: MUC21
• Synonyms: MUC21; mucin 21, cell surface associated; MUC-21; KMQK697; C6orf205; mucin-21
  epiglycanin
• Gene ID: 394263
• mRNA Refseq: NM_001010909
• Protein Refseq: NP_001010909
• MIM: 616991
• UniProt ID: Q5SSG8