Recombinant Human MX1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: MX1-491H
• Product Overview: MX1 MS Standard C13 and N15-labeled recombinant protein (NP_001138397) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 75.3 kDa
• AA Sequence: MVVSEVDIAKADPAAASHPLLLNGD ATVAQKNPGSVAENNLCSQYEEKVR PCIDLIDSLRALGVEQDLALPAIAV IGDQSSGKSSVLEALSGVALPRGSG IVTRCPLVLKLKKLVNEDKWRGKVS YQDYEIEISDASEVEKEINKAQNAI AGEGMGISHELITLEISSRDVPDLT LIDLPGITRVAVGNQPADIGYKIKT LIKKYIQRQETISLVVVPSNVDIAT TEALSMAQEVDPEGDRTIGILTKPD LVDKGTEDKVVDVVRNLVFHLKKGY MIVKCRGQQEIQDQLSLSEALQREK IFFENHPYFRDLLEEGKATVPCLAE KLTSELITHICKSLPLLENQIKETH QRITEELQKYGVDIPEDENEKMFFL IDKINAFNQDITALMQGEETVGEED IRLFTRLRHEFHKWSTIIENNFQEG HKILSRKIQKFENQYRGRELPGFVN YRTFETIVKQQIKALEEPAVDMLHT VTDMVRLAFTDVSIKNFEEFFNLHR TAKSKIEDIRAEQEREGEKLIRLHF QMEQIVYCQDQVYRGALQKVREKEL EEEKKKKSWDFGAFQSSSATDSSME EIFQHLMAYHQEASKRISSHIPLII QFFMLQTYGQQLQKAMLQLLQDKDT YSWLLKERSDTSDKRKFLKERLARL TQARRRLAQFPGTRTRPLEQKLISE EDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: MX1 MX dynamin like GTPase 1 [ Homo sapiens (human) ]
• Official Symbol: MX1
• Synonyms: MX1; myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse); myxovirus (influenza) resistance 1, homolog of murine (interferon inducible protein p78); interferon-induced GTP-binding protein Mx1; IFI 78K; MxA; myxoma resistance protein 1; interferon-regulated resistance GTP-binding protein MxA; MX; IFI78; IFI-78K
• Gene ID: 4599
• mRNA Refseq: NM_001144925
• Protein Refseq: NP_001138397
• MIM: 147150
• UniProt ID: P20591