Recombinant Human MXD3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: MXD3-1631H
• Product Overview: MXD3 MS Standard C13 and N15-labeled recombinant protein (NP_112590) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.
• Molecular Mass: 23.5 kDa
• AA Sequence: MEPLASNIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKKRPPQAPGAQDSGRSVHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERLRSKQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQEELEVDVESLVFGGEAELLRGFVAGQEHSYSHGGGAWLTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: MXD3 MAX dimerization protein 3 [ Homo sapiens (human) ]
• Official Symbol: MXD3
• Synonyms: MXD3; MAX dimerization protein 3; MYX; MAD3; BHLHC13; max dimerization protein 3; Max-associated protein 3; Max-interacting transcriptional repressor MAD3; class C basic helix-loop-helix protein 13; max dimerizer 3
• Gene ID: 83463
• mRNA Refseq: NM_031300
• Protein Refseq: NP_112590
• MIM: 609450
• UniProt ID: Q9BW11