Recombinant Human MYBPC3 protein, MYC/DDK-tagged
Cat.No. : | MYBPC3-19H |
Product Overview : | Recombinant Human MYBPC3 fused with MYC/DDK tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 140.6 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | MYBPC3 myosin binding protein C, cardiac [ Homo sapiens ] |
Official Symbol : | MYBPC3 |
Synonyms : | MYBPC3; myosin binding protein C, cardiac; CMH4, myosin binding protein C, cardiac; myosin-binding protein C, cardiac-type; FHC; MYBP C; C-protein, cardiac muscle isoform; myosin-binding protein C, cardiac; CMH4; MYBP-C; DKFZp779E1762; |
Gene ID : | 4607 |
mRNA Refseq : | NM_000256 |
Protein Refseq : | NP_000247 |
MIM : | 600958 |
UniProt ID : | Q14896 |
Chromosome Location : | 11p11.2 |
Pathway : | Dilated cardiomyopathy, organism-specific biosystem; Dilated cardiomyopathy, conserved biosystem; Hypertrophic cardiomyopathy (HCM), organism-specific biosystem; Hypertrophic cardiomyopathy (HCM), conserved biosystem; Muscle contraction, organism-specific biosystem; Striated Muscle Contraction, organism-specific biosystem; Striated Muscle Contraction, organism-specific biosystem; |
Function : | ATPase activator activity; actin binding; metal ion binding; myosin binding; myosin heavy chain binding; structural constituent of muscle; titin binding; |
Products Types
◆ Recombinant Protein | ||
MYBPC3-3551H | Recombinant Human MYBPC3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Mybpc3-4236M | Recombinant Mouse Mybpc3 Protein, Myc/DDK-tagged | +Inquiry |
MYBPC3-1289H | Recombinant Human MYBPC3 Protein, His-SUMO-tagged | +Inquiry |
MYBPC3-1467R | Recombinant Rat MYBPC3 Protein (645-864 aa), His-tagged | +Inquiry |
MYBPC3-3495R | Recombinant Rat MYBPC3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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