Recombinant Human MYC protein, T7/His-tagged
Cat.No. : | MYC-254H |
Product Overview : | Recombinant Human MYC fused with T7/His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Source : | E. coli |
Species : | Human |
Tag : | T7/His |
Form : | Purified myc protein is supplied in 50 mM Tris, pH 8.0, 250 mM NaCl, 0.75% sarcosine, 10 mM beta mercaptoethanol. |
Molecular Mass : | ~65 kda |
Purity : | >95% |
Applications : | Recombinant c-myc protein is suitable for ELISA or other applications where protein is required. |
Stability : | 6-12 months at –20 centigrade or below. |
Storage : | Short-term: unopened, undiluted liquid vials for less than a week at 4 centigrade and powder at -20 centigrade.Long-term: at –20 centigrade or below in suitable aliquots after reconstitution. Do not freeze and thaw and store working, diluted solutions. |
Concentration : | 1 mg/ml |
Shipping : | 4 centigrade for solutions and room temp for powder. |
Gene Name : | MYC v-myc myelocytomatosis viral oncogene homolog (avian) [ Homo sapiens ] |
Official Symbol : | MYC |
Synonyms : | MYC; v-myc myelocytomatosis viral oncogene homolog (avian); v myc avian myelocytomatosis viral oncogene homolog; myc proto-oncogene protein; bHLHe39; c Myc; proto-oncogene c-Myc; transcription factor p64; class E basic helix-loop-helix protein 39; avian myelocytomatosis viral oncogene homolog; v-myc avian myelocytomatosis viral oncogene homolog; myc-related translation/localization regulatory factor; MRTL; c-Myc; |
Gene ID : | 4609 |
mRNA Refseq : | NM_002467 |
Protein Refseq : | NP_002458 |
MIM : | 190080 |
UniProt ID : | P01106 |
Chromosome Location : | 8q24 |
Pathway : | Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Apoptosis, organism-specific biosystem; Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; C-MYB transcription factor network, organism-specific biosystem; C-MYC pathway, organism-specific biosystem; |
Function : | DNA binding; DNA binding; E-box binding; protein binding; protein complex binding; repressing transcription factor binding; sequence-specific DNA binding transcription factor activity; transcription factor binding; |
Products Types
◆ Recombinant Protein | ||
MYC-5787H | Recombinant Human MYC Protein, GST-tagged | +Inquiry |
MYC-2735R | Recombinant Rhesus Macaque MYC Protein, His (Fc)-Avi-tagged | +Inquiry |
MYC-3498R | Recombinant Rat MYC Protein, His (Fc)-Avi-tagged | +Inquiry |
Myc-4239M | Recombinant Mouse Myc Protein, Myc/DDK-tagged | +Inquiry |
MYC-1461H | Recombinant Human MYC Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
MYC-4039HCL | Recombinant Human MYC 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-1785 | Myc Reporter Kit (Myc Signaling Pathway) | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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- Reviews
Q&As (6)
Ask a questionAbnormal expression of MYC gene may affect the occurrence and progression of cardiovascular diseases such as atherosclerosis by regulating the proliferation of vascular smooth muscle cells and increasing the expression of endothelial cell-specific shear-related proteins.
Because of its important promotion role in pancreatic cancer, MYC gene is regarded as one of the potential targets and drug treatment directions for pancreatic cancer treatment, but specific research and related drugs need to be further verified.
The MYC gene may affect the proliferation of somatic cells by regulating cell cycle progression, such as increasing the S-phase entry of the cell cycle and promoting the G1/S phase transition.
Overexpression and defect of MYC in gastric cancer are associated with the occurrence, progression and prognosis of gastric cancer. MYC translocation and high expression predict a poor prognosis.
MYC gene may be involved in the proliferation and differentiation of hematopoietic stem cells, but the specific mechanism and role still need to be further elucidated.
Abnormal expression of MYC gene may affect tumor progression and prognosis by activating cell cycle constants, apoptosis inhibition, and enhanced cell mobility.
Customer Reviews (3)
Write a reviewThe reproducibility of MYC is very good, and the results remain consistent even after repeated experiments several times, which gives me more confidence in the experimental results.
Stability of this protein was still very good when different chemicals or drugs were added, indicating its excellent anti-interference ability and stability.
Due to stability of MYC in Western blot was very good and even prolonged storage did not affect its performance.
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