"MYD88" Related Products


Recombinant Human MYD88 protein, MYC/DDK-tagged

Cat.No.: MYD88-30H
Product Overview: Recombinant Human MYD88 fused with MYC/DDK tag at C-terminal was expressed in HEK293.
Description: This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
Source: HEK293
Species: Human
Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass: 33.1 kDa
Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration: >50 ug/mL as determined by microplate BCA method
Gene Name: MYD88 myeloid differentiation primary response gene (88) [ Homo sapiens ]
Official Symbol: MYD88
Synonyms: MYD88; myeloid differentiation primary response gene (88); myeloid differentiation primary response protein MyD88; MYD88D;
Gene ID: 4615
mRNA Refseq: NM_002468
Protein Refseq: NP_002459
MIM: 602170
UniProt ID: Q99836
Chromosome Location: 3p22
Function: TIR domain binding; Toll binding; death receptor binding; identical protein binding; protein binding;

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