Recombinant Human MYD88 Protein, His tagged

• Cat.No.: MYD88-1550H
• Product Overview: Recombinant Human MYD88 protein with His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 176-280 aa
• Description: This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
• Form: Liquid
• Molecular Mass: 15 kDa (Calculated)
• Purity: ~95%
• Applications: ELISA, WB
• Storage: Store in working aliquots at -70 centigrade. Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
• Storage Buffer: 1X PBS containing 0.1% SDS and 0.02% NaN3

Gene Information

• Gene Name: MYD88 myeloid differentiation primary response gene (88) [ Homo sapiens (human) ]
• Official Symbol: MYD88
• Synonyms: MYD88; myeloid differentiation primary response gene (88); myeloid differentiation primary response protein MyD88; MYD88D
• Gene ID: 4615
• mRNA Refseq: NM_001172566
• Protein Refseq: NP_001166037
• MIM: 602170
• UniProt ID: Q99836