Recombinant Human MYLK Protein, GST-tagged
Cat.No. : | MYLK-5820H |
Product Overview : | Human MYLK full-length ORF ( ENSP00000355024, 1 a.a. - 992 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3 region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 136.6 kDa |
AA Sequence : | MDFRANLQRQVKPKTVSEEERKVHS PQQVDFRSVLAKKGTSKTPVPEKVP PPKPATPDFRSVLGGKKKLPAENGS SSAETLNAKAVESSKPLSNAQPSGP LKPVGNAKPAETLKPMGNAKPAETL KPMGNAKPDENLKSASKEELKKDVK NDVNCKRGHAGTTDNEKRSESQGTA PAFKQKLQDVHVAEGKKLLLQCQVS SDPPATIIWTLNGKTLKTTKFIILS QEGSLCSVSIEKALPEDRGLYKCVA KNDAGQAECSCQVTVDDAPASENTK APEMKSRRPKSSLPPVLGTESDATV KKKPAPKTPPKAAMPPQIIQFPEDQ KVRAGESVELFGKVTGTQPITCTWM KFRKQIQESEHMKVENSENGSKLTI LAARQEHCGCYTLLVENKLGSRQAQ VNLTVVDKPDPPAGTPCASDIRSSS LTLSWYGSSYDGGSAVQSYSIEIWD SANKTWKELATCRSTSFNVQDLLPD HEYKFRVRAINVYGTSEPSQESELT TVGEKPEEPKDEVEVSDDDEKEPEV DYRTVTINTEQKVSDFYDIEERLGS GKFGQVFRLVEKKTRKVWAGKFFKA YSAKEKENIRQEISIMNCLHHPKLV QCVDAFEEKANIVMVLEIVSGGELF ERIIDEDFELTERECIKYMRQISEG VEYIHKQGIVHLDLKPENIMCVNKT GTRIKLIDFGLARRLENAGSLKVLF GTPEFVAPEVINYEPIGYATDMWSI GVICYILVSGLSPFMGDNDNETLAN VTSATWDFDDEAFDEISDDAKDFIS NLLKKDMKNRLDCTQCLQHPWLMKD TKNMEAKKLSKDRMKKYMARRKWQK TGNAVRAIGRLSSMAMISGLSGRKS STGSPTSPLNAEKLESEEDVSQAFL EAVAEEKPHVKPYFSKTIRDLEVVE GSAARFDCKIEGYPDPEVVWFKDDQ SIRESRHFQIDYDEDGNCSLIISDV CGDDDAKYTCKAVNSLGEATCTAEL IVETMEEGEGEGEEEEE |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | MYLK myosin light chain kinase [ Homo sapiens ] |
Official Symbol : | MYLK |
Synonyms : | MYLK; myosin light chain kinase; myosin, light polypeptide kinase; myosin light chain kinase, smooth muscle; MLCK; MLCK1; MYLK1; smMLCK; smooth muscle myosin light chain kinase; telokin; kinase-related protein; KRP; AAT7; MLCK108; MLCK210; MSTP083; FLJ12216; DKFZp686I10125; |
Gene ID : | 4638 |
mRNA Refseq : | NM_053025 |
Protein Refseq : | NP_444253 |
MIM : | 600922 |
UniProt ID : | Q15746 |
Products Types
◆ Recombinant Protein | ||
Mylk-335M | Recombinant Mouse Mylk Protein, MYC/DDK-tagged | +Inquiry |
MYLK-1509H | Recombinant Human MYLK protein, His & GST-tagged | +Inquiry |
Mylk-3878C | Recombinant Chicken Mylk protein, His-SUMO & Myc-tagged | +Inquiry |
MYLK-5954H | Recombinant Human MYLK protein, His-tagged | +Inquiry |
MYLK-27838TH | Recombinant Human MYLK | +Inquiry |
◆ Lysates | ||
MYLK-4017HCL | Recombinant Human MYLK 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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