| Description : |
MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma. |
| Source : |
HEK293 |
| Species : |
Human |
| Form : |
Lyophilized |
| Molecular Mass : |
32 kDa |
| Protein Length : |
504 |
| AA Sequence : |
MRFFCARCCSFGPEMPAVQLLLLAC LVWDVGARTAQLRKANDQSGRCQYT FSVASPNESSCPEQSQAMSVIHNLQ RDSSTQRLDLEATKARLSSLESLLH QLTLDQAARPQETQEGLQRELGTLR RERDQLETQTRELETAYSNLLRDKS VLEEEKKRLRQENENLARRLESSSQ EVARLRRGQCPQTRDTARAVPPGSR EVSTWNLDTLAFQELKSELTEVPAS RILKESPSGYLRSGEGDTGCGELVW VGEPLTLRTAETITGKYGVWMRDPK PTYPYTQETTWRIDTVGTDVRQVFE YDLISQFMQGYPSKVHILPRPLEST GAVVYSGSLYFQGAESRTVIRYELN TETVKAEKEIPGAGYHGQFPYSWGG YTDIDLAVDEAGLWVIYSTDEAKGA IVLSKLNPENLELEQTWETNIRKQS VANAFIICGTLYTVSSYTSADATVN FAYDTGTGISKTLTIPFKNRYKYSS MIDYNPLEKKLFAWDNLNMVTYDIK LSKM |
| Purity : |
> 98% |
| Applications : |
Migration Assay; WB; ELISA; |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
