Recombinant Human NAGS Protein, MYC/DDK-tagged

• Cat.No.: NAGS-182H
• Product Overview: Recombinant human NAGS protein, fused to MYC/DDK-tag at C-terminal, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia. [provided by RefSeq, Jul 2008].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 58 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: N-acetylglutamate synthase [ Homo sapiens ]
• Official Symbol: NAGS
• Synonyms: AGAS; ARGA
• Gene ID: 162417
• mRNA Refseq: NM_153006.2
• Protein Refseq: NP_694551.1
• MIM: 608300
• UniProt ID: Q8N159