Recombinant Human NANOGP8 cell lysate

• Cat.No.: NANOGP8-2130HCL

Specification

• Species: Human
• Tag: Non
• Description: This locus is a processed pseudogene of the transcription factor NANOG. NANOG plays a central role in regulating self-renewal in pluripotent stem cells and tumor cells. This pseudogene contains an intact open reading frame that could potentially encode a protein similar to NANOG. Although there is no evidence of transcription from this pseudogene, RT-PCR studies suggest that NANOGP8 may be expressed in some cancer cell lines. In vitro studies using a recombinant NANOGP8 protein have shown that the protein localizes to the nucleus and can promote cell proliferation, similar to NANOG.
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: NANOGP8?Nanog homeobox pseudogene 8 [?Homo sapiens?(human) ]
• Official Symbol: NANOGP8
• Synonyms: NANOGP8; Nanog homeobox pseudogene 8; PN8; NANOG; NANOGP1
• UniProt ID: Q6NSW7
• Function: sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity