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Recombinant Human NBN Protein, His-tagged
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Cat.No. : | NBN-001H |
Product Overview : | Purified recombinant protein of Human nibrin (NBN), Pro461-Arg754, with N-terminal His tag, expressed in E. coli. |
Description : | Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Molecular Mass : | 34 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol,1% Sarkosyl. |
Figure : |
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Gene Name : | NBN nibrin [ Homo sapiens (human) ] |
Official Symbol : | NBN |
Synonyms : | NBN; nibrin; ATV; NBS; P95; NBS1; AT-V1; AT-V2; nibrin; Nijmegen breakage syndrome 1 (nibrin); cell cycle regulatory protein p95; p95 protein of the MRE11/RAD50 complex |
Gene ID : | 4683 |
mRNA Refseq : | NM_002485 |
Protein Refseq : | NP_002476 |
MIM : | 602667 |
UniProt ID : | O60934 |
◆ Recombinant Protein
NBN-01H | Recombinant Human NBN Protein, His-tagged | +Inquiry |
NBN-2289Z | Recombinant Zebrafish NBN | +Inquiry |
NBN-3912R | Recombinant Rat NBN Protein | +Inquiry |
NBN-5909C | Recombinant Chicken NBN | +Inquiry |
NBN-2951R | Recombinant Rhesus monkey NBN Protein, His-tagged | +Inquiry |
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◆ Lysates
NBN-3957HCL | Recombinant Human NBN 293 Cell Lysate | +Inquiry |
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