Recombinant Human NDC80 Protein, GST-tagged

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Recombinant Human NDC80 Protein, GST-tagged

NDC80 Related Products

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Cat.No. : NDC80-4899H
Product Overview : Human KNTC2 partial ORF ( AAH35617, 545 a.a. - 642 a.a.) recombinant protein with GST-tag at N-terminal.
Description : HEC is one of several proteins involved in spindle checkpoint signaling. This surveillance mechanism assures correct segregation of chromosomes during cell division by detecting unaligned chromosomes and causing prometaphase arrest until the proper bipolar attachment of chromosomes is achieved.[supplied by OMIM
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 36.19 kDa
AA Sequence : TVNQGLSEAM NELDAVQREY QLVVQTTTEE RRKVGNNLQR LLEMVATHVG SVEKHLEEQI AKVDREYEEC MSEDLSENIK EIRDKYEKKA TLIKSSEE
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue

Gene Name : NDC80 NDC80 kinetochore complex component homolog (S. cerevisiae) [ Homo sapiens ]
Official Symbol : NDC80
Synonyms : NDC80; NDC80 kinetochore complex component homolog (S. cerevisiae); highly expressed in cancer, rich in leucine heptad repeats (yeast) , kinetochore associated 2 , KNTC2; kinetochore protein NDC80 homolog; HEC; HEC1; hsNDC80; TID3; kinetochore associated 2; kinetochore protein Hec1; kinetochore-associated protein 2; highly expressed in cancer protein; retinoblastoma-associated protein HEC; NDC80 homolog, kinetochore complex component; highly expressed in cancer, rich in leucine heptad repeats; KNTC2; HsHec1;
Gene ID : 10403
mRNA Refseq : NM_006101
Protein Refseq : NP_006092
MIM : 607272
UniProt ID : O14777

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