Recombinant Human NDC80 protein, MYC/DDK-tagged
Cat.No. : | NDC80-18H |
Product Overview : | Recombinant Human NDC80 fused with MYC/DDK tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 73.7 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | NDC80 NDC80 kinetochore complex component homolog (S. cerevisiae) [ Homo sapiens ] |
Official Symbol : | NDC80 |
Synonyms : | NDC80; NDC80 kinetochore complex component homolog (S. cerevisiae); highly expressed in cancer, rich in leucine heptad repeats (yeast) , kinetochore associated 2 , KNTC2; kinetochore protein NDC80 homolog; HEC; HEC1; hsNDC80; TID3; kinetochore associated 2; kinetochore protein Hec1; kinetochore-associated protein 2; highly expressed in cancer protein; retinoblastoma-associated protein HEC; NDC80 homolog, kinetochore complex component; highly expressed in cancer, rich in leucine heptad repeats; KNTC2; HsHec1; |
Gene ID : | 10403 |
mRNA Refseq : | NM_006101 |
Protein Refseq : | NP_006092 |
MIM : | 607272 |
UniProt ID : | O14777 |
Chromosome Location : | 18p11.31 |
Pathway : | Aurora B signaling, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; DNA Replication, organism-specific biosystem; M Phase, organism-specific biosystem; Mitotic M-M/G1 phases, organism-specific biosystem; Mitotic Prometaphase, organism-specific biosystem; |
Function : | protein binding; |
Products Types
◆ Recombinant Protein | ||
NDC80-474C | Recombinant Cynomolgus Monkey NDC80 Protein, His (Fc)-Avi-tagged | +Inquiry |
NDC80-2782R | Recombinant Rhesus Macaque NDC80 Protein, His (Fc)-Avi-tagged | +Inquiry |
NDC80-4899H | Recombinant Human NDC80 Protein, GST-tagged | +Inquiry |
NDC80-5949M | Recombinant Mouse NDC80 Protein, His (Fc)-Avi-tagged | +Inquiry |
NDC80-10493M | Recombinant Mouse NDC80 Protein | +Inquiry |
◆ Lysates | ||
NDC80-952HCL | Recombinant Human NDC80 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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