Recombinant Human NDE1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human NDE1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : NDE1-789H
Product Overview : NDE1 MS Standard C13 and N15-labeled recombinant protein (NP_001137451) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe cognitive disability. Alternative splicing results in multiple transcript variants.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 37.7 kDa
AA Sequence : MEDSGKTFSS EEEEANYWKD LAMTYKQRAE NTQEELREFQ EGSREYEAEL ETQLQQIETR NRDLLSENNR LRMELETIKE KFEVQHSEGY RQISALEDDL AQTKAIKDQL QKYIRELEQA NDDLERAKRA TIMSLEDFEQ RLNQAIERNA FLESELDEKE NLLESVQRLK DEARDLRQEL AVQQKQEKPR IPMPSSVEAE RTDTAVQATG SVPSTPIAHR GPSSSLNTPG SFRRGLDDST GGTPLTPAAR ISALNIVGDL LRKVGALESK LASCRNLVYD QSPNRTGGPA SGRSSKNRDG GERRPSSTSV PLGDKGLDTS CRWLSKSTTR SSSSCTRTRP LEQKLISEED LAANDILDYK DDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : NDE1 nudE neurodevelopment protein 1 [ Homo sapiens (human) ]
Official Symbol : NDE1
Synonyms : NDE1; nudE nuclear distribution E homolog 1 (A. nidulans); nudE nuclear distribution gene E homolog 1 (A. nidulans); nuclear distribution protein nudE homolog 1; FLJ20101; NUDE; nudE nuclear distribution gene E homolog 1; LIS1-interacting protein NUDE1, rat homolog; LIS4; NUDE1; HOM-TES-87;
Gene ID : 54820
mRNA Refseq : NM_001143979
Protein Refseq : NP_001137451
MIM : 609449
UniProt ID : Q9NXR1

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