Recombinant Human NECTIN3 protein, His-Avi-tagged

• Cat.No.: NECTIN3-093H
• Product Overview: Recombinant Human Nectin-3 Protein is expressed from mammalian with His and Avi Tag at the C-terminal. It contains Gly 58-Asp 400.

Specification

• Description: The Nectin family has at least four members (Nectin-1‑4), all of which show alternate splicing, a transmembrane (TM) region (except for Nectin-1 gamma ), and three extracellular Ig-domains. Nectins are highly homologous to the human receptor for poliovirus, and as such, have been alternatively-named poliovirus receptor-related proteins. They do not, however, appear to bind poliovirus. Nectin-3 (also named PRR3, CD113, and PVRL3) is an 83 kDa, type I TM glycoprotein. Its precursor is 549 amino acids (aa) in length. It contains an extended signal sequence of 57 aa, an extracellular domain (ECD) of 347 aa, a transmembrane segment of 21 aa (aa 405-425), and a cytoplasmic region of 124 amino acids.
• Source: HEK293
• Species: Human
• Tag: His-Avi
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 40.6 KDa. Due to glycosylation, the protein migrates to 68-82 KDa based on Bis-Tris PAGE result.
• Protein length: Gly 58-Asp 400
• Endotoxin: Less than 0.1 EU per ug by the LAL method.
• Purity: > 95% as determined by Tris-Bis PAGE
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: NECTIN3 nectin cell adhesion molecule 3 [ Homo sapiens (human) ]
• Official Symbol: NECTIN3
• Synonyms: CD113 antigen; CD113; CDw113FLJ90624; DKFZp566B0846; nectin 3; Nectin3; Nectin-3; poliovirus receptor-related 3; poliovirus receptor-related protein 3; PPR3; PRR3CD113; PVRL3; PVRR3
• Gene ID: 25945
• mRNA Refseq: NM_001243286.2
• Protein Refseq: NP_001230215.1
• MIM: 607147
• UniProt ID: Q9NQS3