Recombinant Human NECTIN4 Protein, MYC/DDK-tagged

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Recombinant Human NECTIN4 Protein, MYC/DDK-tagged

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Cat.No. : NECTIN4-591H
Product Overview : Recombinant human NECTIN4 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
Description : This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.[provided by RefSeq, Jan 2011].
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass : 55.3 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : nectin cell adhesion molecule 4[ Homo sapiens ]
Official Symbol : NECTIN4
Synonyms : EDSS1; LNIR; nectin-4; PRR4; PVRL4
Gene ID : 81607
Protein Refseq : NP_112178
MIM : 609607
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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