Recombinant Human NELL2 protein, His & T7-tagged

• Cat.No.: NELL2-1915H
• Product Overview: Recombinant Human NELL2 aa. (Pro64~Lys331 (Accession # Q99435)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Description: The protein encoded by this gene is a glycoprotein containing several von Willebrand factor C domains and epidermal growth factor (EGF)-like domains. The encoded protein acts as a homotrimer and is found in the cytoplasm. Several variants encoding a few different isoforms exist, and at least one isoform appears to be a secreted protein. Studies in mouse suggest that this protein plays a role in neural cell growth and differentiation as well as in oncogenesis.
• Source: E. coli
• Species: Human
• Tag: His & T7
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 34.4kDa
• Protein length: Pro64~Lys331 (Accession # Q99435)
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >90%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Isoelectric Point: 8.5

Gene Information

• Gene Name: NELL2 neural EGFL like 2 [ Homo sapiens (human) ]
• Official Symbol: NELL2
• Synonyms: NELL2; neural EGFL like 2; NRP2; protein kinase C-binding protein NELL2; NEL-like protein 2; NEL-related protein 2; neural epidermal growth factor-like 2
• Gene ID: 4753
• mRNA Refseq: NM_001145107.1
• Protein Refseq: NP_001138579.1
• UniProt ID: Q99435