Recombinant Human NFKB2 protein, His/MBP-tagged

• Cat.No.: NFKB2-306H
• Product Overview: Recombinant Human NFKB2(698-900 aa) fused with His/MBP tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His&MBP
• Protein Length: 698-900 aa
• Description: This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.
• Form: Liquid in PBS
• Purity: SDS-PAGE >90%
• Applications: WB Positive Control
• Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
• Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) [ Homo sapiens ]
• Official Symbol: NFKB2
• Synonyms: NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100); nuclear factor NF-kappa-B p100 subunit; LYT 10; NF kB2; p52; p105; oncogene Lyt-10; DNA-binding factor KBF2; lymphocyte translocation chromosome 10 protein; nuclear factor of kappa light chain gene enhancer in B-cells 2; H2TF1; LYT10; LYT-10; NF-kB2
• Gene ID: 4791
• mRNA Refseq: NM_001077493
• Protein Refseq: NP_001070961
• MIM: 164012
• UniProt ID: Q00653