Recombinant Human NLRP13 Protein, GST-tagged

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Recombinant Human NLRP13 Protein, GST-tagged

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Cat.No. : NLRP13-5920H
Product Overview : Human NLRP13 full-length ORF ( AAI48743.1, 1 a.a. - 1043 a.a.) recombinant protein with GST-tag at N-terminal.
Description : NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP13, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 141.68 kDa
AA Sequence : MNFSVITCPN GGTNQGLLPY LMALDQYQLE EFKLCLEPQQ LMDFWSAPQG HFPRIPWANL RAADPLNLSF LLDEHFPKGQ AWKVVLGIFQ TMNLTSLCEK VRAEMKENVQ TQELQDPTQE DLEMLEAAAG NMQTQGCQDP NQEELDELEE ETGNVQAQGC QDPNQEEPEM LEEADHRRKY RENMKAELLE TWDNISWPKD HVYIRNTSKD EHEELQRLLD PNRTRAQAQT IVLVGRAGVG KTTLAMQAML HWANGVLFQQ RFSYVFYLSC HKIRYMKETT FAELISLDWP DFDAPIEEFM SQPEKLLFII DGFEEIIISE SRSESLDDGS PCTDWYQELP VTKILHSLLK KELVPLATLL ITIKTWFVRD LKASLVNPCF VQITGFTGDD LRVYFMRHFD DSSEVEKILQ QLRKNETLFH SCSAPMVCWT VCSCLKQPKV RYYDLQSITQ TTTSLYAYFF SNLFSTAEVD LADDSWPGQW RALCSLAIEG LWSMNFTFNK EDTEIEGLEV PFIDSLYEFN ILQKINDCGG CTTFTHLSFQ EFFAAMSFVL EEPREFPPHS TKPQEMKMLL QHVLLDKEAY WTPVVLFFFG LLNKNIAREL EDTLHCKISP RVMEELLKWG EELGKAESAS LQFHILRLFH CLHESQEEDF TKKMLGRIFE VDLNILEDEE LQASSFCLKH CKRLNKLRLS VSSHILERDL EILETSKFDS RMHAWNSICS TLVTNENLHE LDLSNSKLHA SSVKGLCLAL KNPRCKVQKL TCKSVTPEWV LQDLIIALQG NSKLTHLNFS SNKLGMTVPL ILKALRHSAC NLKYLCLEKC NLSAASCQDL ALFLTSIQHV TRLCLGFNRL QDDGIKLLCA ALTHPKCALE RLELWFCQLA APACKHLSDA LLQNRSLTHL NLSKNSLRDE GVKFLCEALG RPDGNLQSLN LSGCSFTREG CGELANALSH NHNVKILDLG ENDLQDDGVK LLCEALKPHR ALHTLGLAKC NLTTACCQHL FSVLSSSKSL VNLNLLGNEL DTDGVKMLCK ALKKSTCRLQ KLG
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing: :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : NLRP13 NLR family, pyrin domain containing 13 [ Homo sapiens ]
Official Symbol : NLRP13
Synonyms : NLRP13; NLR family, pyrin domain containing 13; NACHT, leucine rich repeat and PYD containing 13 , NALP13; NACHT, LRR and PYD domains-containing protein 13; CLR19.7; NOD14; nucleotide binding oligomerization domain; leucine rich repeat and pyrin domain containing 13; PAN13; NACHT, LRR and PYD containing protein 13; NACHT, leucine rich repeat and PYD containing 13; nucleotide-binding oligomerization domain protein 14; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 13; NALP13;
Gene ID : 126204
mRNA Refseq : NM_176810
Protein Refseq : NP_789780
MIM : 609660
UniProt ID : Q86W25

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