Recombinant Human NMI Protein, GST-tagged

• Cat.No.: NMI-5935H
• Product Overview: Human NMI full-length ORF ( AAH21987.1, 1 a.a. - 307 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 61.5 kDa
• AA Sequence: MEADKDDTQQILKEHSPDEFIKDEQ NKGLIDEITKKNIQLRKEIQKLETE LQEATKEFQIKEDIPETKMKFLSVE TPENDSQLSNISCSFQVSSKVPYEI QKGQALITFEKEEVAQNVVSMSKHH VQIKDVNLEVTAKPVPLNSGVRFQV YVEVSKMKINVTEIPDTLREDQMRD KLELSFSKSRNGGGEVDRVDYDRQS GSAVITFVEIGVADKILKKKEYPLY INQTCHRVTVSPYTEIHLKKYQIFS GTSKRTVLLTGMEGIQMDEEIVEDL INIHFQRAKNGGGEVDVVKCSLGQP HIAYFEE
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: NMI N-myc (and STAT) interactor [ Homo sapiens ]
• Official Symbol: NMI
• Synonyms: NMI; N-myc (and STAT) interactor; N-myc-interactor; N-myc interactor
• Gene ID: 9111
• mRNA Refseq: NM_004688
• Protein Refseq: NP_004679
• MIM: 603525
• UniProt ID: Q13287