Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at BIO-Europe Spring|March 18–20, 2024|Booth #34

Recombinant Human NONO protein, MYC/DDK-tagged

Cat.No. : NONO-853H
Product Overview : Recombinant Human NONO, transcript variant 2, fused with MYC/DDK tag at C-terminal was expressed in HEK293.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes exist on Chromosomes 2 and 16.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 54.1 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : NONO non-POU domain containing, octamer-binding [ Homo sapiens ]
Official Symbol : NONO
Synonyms : NONO; non-POU domain containing, octamer-binding; non POU domain containing, octamer binding; non-POU domain-containing octamer-binding protein; NMT55; non Pou domain containing octamer (ATGCAAAT) binding protein; NRB54; Nuclear RNA binding protein; 54 kD; P54; P54NRB; p54(nrb); 55 kDa nuclear protein; 54 kDa nuclear RNA- and DNA-binding protein; DNA-binding p52/p100 complex, 52 kDa subunit; non-POU domain-containing octamer (ATGCAAAT) binding protein;
Gene ID : 4841
mRNA Refseq : NM_007363
Protein Refseq : NP_031389
MIM : 300084
UniProt ID : Q15233
Chromosome Location : Xq13.1
Pathway : Circadian rhythm pathway, organism-specific biosystem; mRNA processing, organism-specific biosystem;
Function : DNA binding; RNA binding; identical protein binding; nucleotide binding; protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (6)

Ask a question
In which tissues or organs is NONO protein highly expressed? 06/15/2022

This protein is widely expressed in a variety of tissues and organs, including the brain, heart, liver, kidneys, and muscles.

Is NONO protein involved in RNA splicing regulation? 03/24/2022

Yes, NONO protein is involved in the regulation of RNA splicing and plays an important role in the splicing process by interacting with other proteins.

Is NONO protein involved in liver function? 02/08/2022

NONO protein is expressed in the liver and is involved in the regulation of signaling pathways related to liver function. However, further research is needed to determine its specific role.

Is there a relationship between NONO protein and DNA damage repair? 01/10/2022

NONO protein interacts with DNA repair-related proteins and is involved in the repair process of DNA double-strand breaks.

What is the role of NONO protein in neurological diseases? 11/30/2021

The protein has been implicated in some neurological diseases, such as motor neuron disease, but its specific role and mechanism still need to be further studied.

What diseases are NONO associated with? 01/21/2021

NONO protein has been implicated in a variety of diseases, including leukemia, neurological diseases such as motor neuron disease, and progeria.

Customer Reviews (3)

Write a review
Reviews
08/08/2023

    The stability of NONO has good adaptability under different temperature and pH conditions.

    04/01/2022

      NONO has important application value in the field of drug research and development, and has achieved certain research results.

      04/01/2020

        Experiments with NONO are easy to use and do not require complex procedures.

        Ask a Question for All NONO Products

        Required fields are marked with *

        My Review for All NONO Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends