Recombinant Human NPHS1 Protein (23-257 aa), His-tagged
Cat.No. : | NPHS1-689H |
Product Overview : | Recombinant Human NPHS1 Protein (23-257 aa) is produced by E. coli expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Cell Adhesion. Protein Description: Partial. |
- Specification
- Gene Information
- Related Products
Description : | Ses to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Tris-based buffer, 50% glycerol |
Molecular Mass : | 29.1 kDa |
Protein length : | 23-257 aa |
AA Sequence : | QLAIPASVPRGFWALPENLTVVEGA SVELRCGVSTPGSAVQWAKDGLLLG PDPRIPGFPRYRLEGDPARGEFHLH IEACDLSDDAEYECQVGRSEMGPEL VSPRVILSILVPPKLLLLTPEAGTM VTWVAGQEYVVNCVSGDAKPAPDIT ILLSGQTISDISANVNEGSQQKLFT VEATARVTPRSSDNRQLLVCEASSP ALEAPIKASFTVNVLFPPGPPVIEW PGLDEGHVRA |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA with concentration instruction is sent along with the products. |
Gene Name : | NPHS1 nephrosis 1, congenital, Finnish type (nephrin) [ Homo sapiens ] |
Official Symbol : | NPHS1 |
Synonyms : | NPHS1; nephrin; CNF; NPHN; |
Gene ID : | 4868 |
mRNA Refseq : | NM_004646 |
Protein Refseq : | NP_004637 |
MIM : | 602716 |
UniProt ID : | O60500 |
Products Types
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionMutations in the NPHS1 gene cause a decrease in nephrin protein and abnormal distribution.
NPHS1 expression is downregulated in diabetic nephropathy tissues.
LPS silences NPHS1 gene expression through histone H3K9 dimethylation.
Expression of lncRNA CRNDE negative correlation with NPHS1.
NPHS1 is closely associated with the study of multiple kidney diseases.
Customer Reviews (3)
Write a reviewProfessional personnel to provide after-sales service, experimental results are guaranteed.
High protein concentration, good quality, worth buying.
The technicians were very professional and suggested improvements to my experimental program, which allowed the experiment to go smoothly.
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