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Recombinant Human NPHS1 Protein (23-257 aa), His-tagged

Cat.No. : NPHS1-689H
Product Overview : Recombinant Human NPHS1 Protein (23-257 aa) is produced by E. coli expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Cell Adhesion. Protein Description: Partial.
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  • Gene Information
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Description : Ses to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion.
Source : E. coli
Species : Human
Tag : His
Form : Tris-based buffer, 50% glycerol
Molecular Mass : 29.1 kDa
Protein length : 23-257 aa
AA Sequence : QLAIPASVPRGFWALPENLTVVEGA SVELRCGVSTPGSAVQWAKDGLLLG PDPRIPGFPRYRLEGDPARGEFHLH IEACDLSDDAEYECQVGRSEMGPEL VSPRVILSILVPPKLLLLTPEAGTM VTWVAGQEYVVNCVSGDAKPAPDIT ILLSGQTISDISANVNEGSQQKLFT VEATARVTPRSSDNRQLLVCEASSP ALEAPIKASFTVNVLFPPGPPVIEW PGLDEGHVRA
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with concentration instruction is sent along with the products.
Gene Name : NPHS1 nephrosis 1, congenital, Finnish type (nephrin) [ Homo sapiens ]
Official Symbol : NPHS1
Synonyms : NPHS1; nephrin; CNF; NPHN;
Gene ID : 4868
mRNA Refseq : NM_004646
Protein Refseq : NP_004637
MIM : 602716
UniProt ID : O60500

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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What is the relationship between NPHS1 and nephrin protein expression? 11/09/2022

Mutations in the NPHS1 gene cause a decrease in nephrin protein and abnormal distribution.

How is NPHS1 expressed in diabetic nephropathy tissues? 03/12/2022

NPHS1 expression is downregulated in diabetic nephropathy tissues.

What is the relationship between LPS and NPHS1? 07/20/2021

LPS silences NPHS1 gene expression through histone H3K9 dimethylation.

How is the lncRNA CRNDE related to NPHS1? 04/11/2021

Expression of lncRNA CRNDE negative correlation with NPHS1.

What diseases is NPHS1 involved in? 03/13/2021

NPHS1 is closely associated with the study of multiple kidney diseases.

Customer Reviews (3)

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Reviews
01/27/2023

    Professional personnel to provide after-sales service, experimental results are guaranteed.

    08/12/2022

      High protein concentration, good quality, worth buying.

      01/02/2022

        The technicians were very professional and suggested improvements to my experimental program, which allowed the experiment to go smoothly.

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