"NPM1/ALK" Related Products

Recombinant Human NPM1/ALK Protein, Active

Cat.No.: NPM1/ALK-02H
Product Overview: Recombinant Human NPM1/ALK was expressed in Insect cells.
Description: Human pathological fusionprotein NPM1 ALK, full length, amino acids M1-P680 (as in NCBI/Protein entry AAA58698.1) with a F1174Lmutation, untagged, expressed in Sf9 insect cells.
Source: Insect cells
Species: Human
Form: 50 mM HEPES pH 7.5, 100 mM NaCl, 5 mM DTT, 20% glycerol
Bio-activity: 182 pmol/µg×min
Molecular Mass: 75,661 Da
AA Sequence: GPLALHIVEAEAMN YEGSPIKVTL ATLKMSVQPT VSLGGFEITP PVVLRLKCGS GPVHISGQHL MEDSMD MDMSPLRPQN YLFGCELKAD KDYHFKVDND ENEHQLSLRT VSLGAGAKDEVVYRRKHQEL QAMQMELQSP EYKLSKLRTS TIMTDYNPNY CFAGKTSSIS DLKEVPRKNI TLIRGLGHGA FGEVYEGQVS GMPNDPSPLQ VAVKTLPEVC SEQDELDFLM EALIISKLNHQNIVRCIGVS LQSLPRFILL ELMAGGDLKS FLRETRPRPS QPSSLAMLDL LHVARDIACG CQYLEENHFI HRDIAARNCL LTCPGPGRVA KIGDFGMARD IYRASYYRKG GCAMLPVKWMPPEAFMEGIF TSKTDTWSFG VLLWEIFSLG YMPYPSKSNQ EVLEFVTSGG RMDPPKNCPG PVYRIMTQCW QHQPEDRPNF AIILERIEYC TQDPDVINTA LPIEYGPLVE EEEKVPVRPKDPEGVPPLLV SQQAKREEER SPAAPPPLPT TSSGKAAKKP TAAEVSVRVP RGPAVEGGHV NMAFSQSNPP SELHRVHGSR NKPTSLWNPT YGSWFTEKPT KKNNPIAKKE PHERGNLGLEGSCTVPPNVA TGRLPGASLL LEPSSLTANM KEVPLFRLRH FPCGNVNYGY QQQGLPLEAA TAPGAGHYED TILKSKNSMN QPGP
Storage: Storage at -80 centigrade. Avoid repeated freeze-thaw cycles!
Concentration: 0.151 µg/µl (Bradford method using BSA as standard protein)
Gene Name: NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) [ Homo sapiens ]
Official Symbol: NPM1
Synonyms: NPM1; nucleophosmin (nucleolar phosphoprotein B23, numatrin); nucleophosmin; B23; NPM; nucleolar phosphoprotein B23; nucleophosmin/nucleoplasmin family; member 1; numatrin; nucleolar protein NO38; nucleophosmin/nucleoplasmin family, member 1; MGC104254;
Gene ID: 4869
mRNA Refseq: NM_001037738
Protein Refseq: NP_001032827
MIM: 164040
UniProt ID: P06748
Chromosome Location: 5q35.1
Pathway: Aurora B signaling, organism-specific biosystem; BARD1 signaling events, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem; Deposition of New CENPA-containing Nucleosomes at the Centromere, organism-specific biosystem; Disease, organism-specific biosystem; HIF-1-alpha transcription factor network, organism-specific biosystem;
Function: NF-kappaB binding; NF-kappaB binding; RNA binding; Tat protein binding; histone binding; nucleic acid binding; protein binding; protein heterodimerization activity; protein homodimerization activity; protein kinase binding; ribosomal large subunit binding; ribosomal small subunit binding; transcription coactivator activity; unfolded protein binding; unfolded protein binding;

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