Recombinant Human NPR1 Protein, GST-tagged
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Cat.No. : | NPR1-6043H |
Product Overview : | Human NPR1 partial ORF ( AAH63304, 147 a.a. - 247 a.a.) recombinant protein with GST-tag at N-terminal. |
Description : | Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994 [PubMed 7982997]). The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961). Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295), respectively).[supplied by OMIM |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 36.74 kDa |
AA Sequence : | GVKDEYALTT RAGPSYAKLG DFVAALHRRL GWERQALMLY AYRPGDEEHC FFLVEGLFMR VRDRLNITVD HLEFAEDDLS HYTRLLRTMP RKGRVIYICS S |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Quality Control Testing: : |
![]() 12.5% SDS-PAGE Stained with Coomassie Blue. |
Gene Name : | NPR1 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) [ Homo sapiens ] |
Official Symbol : | NPR1 |
Synonyms : | NPR1; natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A); ANPRA, NPRA; atrial natriuretic peptide receptor 1; ANPa; GUCY2A; GC-A; ANP-A; NPR-A; ANPR-A; guanylate cyclase A; natriuretic peptide receptor A; atrionatriuretic peptide receptor A; natriuretic peptide A type receptor; atrial natriuretic peptide receptor type A; NPRA; ANPRA; GUC2A; |
Gene ID : | 4881 |
mRNA Refseq : | NM_000906 |
Protein Refseq : | NP_000897 |
MIM : | 108960 |
UniProt ID : | P16066 |
◆ Recombinant Protein
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NPR1-28546TH | Recombinant Human NPR1 | +Inquiry |
NPR1-1299H | Recombinant Human NPR1 Protein, His-tagged | +Inquiry |
NPR1-150H | Recombinant Human NPR1 | +Inquiry |
Npr1-3769M | Recombinant Mouse Npr1, His-tagged | +Inquiry |
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◆ Lysates
NPR1-3733HCL | Recombinant Human NPR1 293 Cell Lysate | +Inquiry |
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