Recombinant Human NPR1 Protein, GST-tagged
Cat.No. : | NPR1-6043H |
Product Overview : | Human NPR1 partial ORF ( AAH63304, 147 a.a. - 247 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994 [PubMed 7982997]). The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961). Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295), respectively).[supplied by OMIM |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 36.74 kDa |
AA Sequence : | GVKDEYALTTRAGPSYAKLGDFVAA LHRRLGWERQALMLYAYRPGDEEHC FFLVEGLFMRVRDRLNITVDHLEFA EDDLSHYTRLLRTMPRKGRVIYICS S |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | NPR1 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) [ Homo sapiens ] |
Official Symbol : | NPR1 |
Synonyms : | NPR1; natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A); ANPRA, NPRA; atrial natriuretic peptide receptor 1; ANPa; GUCY2A; GC-A; ANP-A; NPR-A; ANPR-A; guanylate cyclase A; natriuretic peptide receptor A; atrionatriuretic peptide receptor A; natriuretic peptide A type receptor; atrial natriuretic peptide receptor type A; NPRA; ANPRA; GUC2A; |
Gene ID : | 4881 |
mRNA Refseq : | NM_000906 |
Protein Refseq : | NP_000897 |
MIM : | 108960 |
UniProt ID : | P16066 |
Products Types
◆ Recombinant Protein | ||
Npr1-4476M | Recombinant Mouse Npr1 Protein, Myc/DDK-tagged | +Inquiry |
NPR1-3708R | Recombinant Rat NPR1 Protein, His (Fc)-Avi-tagged | +Inquiry |
NPR1-1531H | Recombinant Human NPR1 Protein, His (Fc)-Avi-tagged | +Inquiry |
NPR1-6171M | Recombinant Mouse NPR1 Protein, His (Fc)-Avi-tagged | +Inquiry |
NPR1-2503H | Recombinant Human NPR1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
NPR1-3733HCL | Recombinant Human NPR1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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