Recombinant Human NPTX2 Protein, GST-tagged

• Cat.No.: NPTX2-6051H
• Product Overview: Human NPTX2 full-length ORF ( NP_002514.1, 1 a.a. - 431 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 73.4 kDa
• AA Sequence: MLALLAASVALAVAAGAQDSPAPGS RFVCTALPPEAVHAGCPLPAMPMQG GAQSPEEELRAAVLQLRETVVQQKE TLGAQREAIRELTGKLARCEGLAGG KARGAGATGKDTMGDLPRDPGHVVE QLSRSLQTLKDRLESLEHQLRANVS NAGLPGDFREVLQQRLGELERQLLR KVAELEDEKSLLHNETSAHRQKTES TLNALLQRVTELERGNSAFKSPDAF KVSLPLRTNYLYGKIKKTLPELYAF TICLWLRSSASPGIGTPFSYAVPGQ ANEIVLIEWGNNPIELLINDKVAQL PLFVSDGKWHHICVTWTTRDGMWEA FQDGEKLGTGENLAPWHPIKPGGVL ILGQEQDTVGGRFDATQAFVGELSQ FNIWDRVLRAQEIVNIANCSTNMPG NIIPWVDNNVDVFGGASKWPVETCE ERLLDL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: NPTX2 neuronal pentraxin II [ Homo sapiens (human) ]
• Official Symbol: NPTX2
• Synonyms: NPTX2; NP2; NARP; NP-II; neuronal pentraxin II; neuronal pentraxin-2; apexin; neuronal activity-regulated pentaxin
• Gene ID: 4885
• mRNA Refseq: NM_002523
• Protein Refseq: NP_002514
• MIM: 600750
• UniProt ID: P47972