Recombinant Human NPTX2 Protein, GST-tagged

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Recombinant Human NPTX2 Protein, GST-tagged

NPTX2 Related Products

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Cat.No. : NPTX2-6051H
Product Overview : Human NPTX2 full-length ORF ( NP_002514.1, 1 a.a. - 431 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 73.4 kDa
AA Sequence : MLALLAASVA LAVAAGAQDS PAPGSRFVCT ALPPEAVHAG CPLPAMPMQG GAQSPEEELR AAVLQLRETV VQQKETLGAQ REAIRELTGK LARCEGLAGG KARGAGATGK DTMGDLPRDP GHVVEQLSRS LQTLKDRLES LEHQLRANVS NAGLPGDFRE VLQQRLGELE RQLLRKVAEL EDEKSLLHNE TSAHRQKTES TLNALLQRVT ELERGNSAFK SPDAFKVSLP LRTNYLYGKI KKTLPELYAF TICLWLRSSA SPGIGTPFSY AVPGQANEIV LIEWGNNPIE LLINDKVAQL PLFVSDGKWH HICVTWTTRD GMWEAFQDGE KLGTGENLAP WHPIKPGGVL ILGQEQDTVG GRFDATQAFV GELSQFNIWD RVLRAQEIVN IANCSTNMPG NIIPWVDNNV DVFGGASKWP VETCEERLLD L
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing: :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : NPTX2 neuronal pentraxin II [ Homo sapiens (human) ]
Official Symbol : NPTX2
Synonyms : NPTX2; NP2; NARP; NP-II; neuronal pentraxin II; neuronal pentraxin-2; apexin; neuronal activity-regulated pentaxin
Gene ID : 4885
mRNA Refseq : NM_002523
Protein Refseq : NP_002514
MIM : 600750
UniProt ID : P47972

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