Recombinant Human NR1I2 Protein, GST-tagged
Cat.No. : | NR1I2-6073H |
Product Overview : | Human NR1I2 full-length ORF ( NP_003880.3, 1 a.a. - 434 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 76.2 kDa |
AA Sequence : | MEVRPKESWNHADFVHCEDTESVPG KPSVNADEEVGGPQICRVCGDKATG YHFNVMTCEGCKGFFRRAMKRNARL RCPFRKGACEITRKTRRQCQACRLR KCLESGMKKEMIMSDEAVEERRALI KRKKSERTGTQPLGVQGLTEEQRMM IRELMDAQMKTFDTTFSHFKNFRLP GVLSSGCELPESLQAPSREEAAKWS QVRKDLCSLKVSLQLRGEDGSVWNY KPPADSGGKEIFSLLPHMADMSTYM FKGIISFAKVISYFRDLPIEDQISL LKGAAFELCQLRFNTVFNAETGTWE CGRLSYCLEDTAGGFQQLLLEPMLK FHYMLKKLQLHEEEYVLMQAISLFS PDRPGVLQHRVVDQLQEQFAITLKS YIECNRPQPAHRFLFLKIMAMLTEL RSINAQHTQRLLRIQDIHPFATPLM QELFGITGS |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | NR1I2 nuclear receptor subfamily 1, group I, member 2 [ Homo sapiens ] |
Official Symbol : | NR1I2 |
Synonyms : | NR1I2; nuclear receptor subfamily 1, group I, member 2; nuclear receptor subfamily 1 group I member 2; BXR; ONR1; PAR2; PXR; SXR; pregnane X receptor; orphan nuclear receptor PXR; orphan nuclear receptor PAR1; steroid and xenobiotic receptor; pregnane X nuclear receptor variant 2; PAR; PRR; SAR; PAR1; PARq; |
Gene ID : | 8856 |
mRNA Refseq : | NM_003889 |
Protein Refseq : | NP_003880 |
MIM : | 603065 |
UniProt ID : | O75469 |
Products Types
◆ Recombinant Protein | ||
NR1I2-6181M | Recombinant Mouse NR1I2 Protein, His (Fc)-Avi-tagged | +Inquiry |
NR1I2-3724R | Recombinant Rat NR1I2 Protein, His (Fc)-Avi-tagged | +Inquiry |
NR1I2-2912R | Recombinant Rhesus Macaque NR1I2 Protein, His (Fc)-Avi-tagged | +Inquiry |
NR1I2-1537H | Recombinant Human NR1I2 Protein, His (Fc)-Avi-tagged | +Inquiry |
NR1I2-1300H | Recombinant Human NR1I2 Protein, His-SUMO/MYC-tagged | +Inquiry |
◆ Lysates | ||
NR1I2-3718HCL | Recombinant Human NR1I2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket