Recombinant Human NTHL1 protein, MYC/DDK-tagged
Cat.No. : | NTHL1-20H |
Product Overview : | Recombinant Human NTHL1 fused with MYC/DDK tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a DNA N-glycosylase of the endonuclease III family. Like a similar protein in E. coli, the encoded protein has DNA glycosylase activity on DNA substrates containing oxidized pyrimidine residues and has apurinic/apyrimidinic lyase activity. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 34.2 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Notes : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | NTHL1 nth endonuclease III-like 1 (E. coli) [ Homo sapiens ] |
Official Symbol : | NTHL1 |
Synonyms : | NTHL1; nth endonuclease III-like 1 (E. coli); nth (E.coli endonuclease III) like 1; endonuclease III-like protein 1; NTH1; OCTS3; |
Gene ID : | 4913 |
mRNA Refseq : | NM_002528 |
Protein Refseq : | NP_002519 |
MIM : | 602656 |
UniProt ID : | P78549 |
Chromosome Location : | 16p13.3 |
Pathway : | Base Excision Repair, organism-specific biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Base-Excision Repair, AP Site Formation, organism-specific biosystem; Base-free sugar-phosphate removal via the single-nucleotide replacement pathway, organism-specific biosystem; Cleavage of the damaged pyrimidine, organism-specific biosystem; DNA Repair, organism-specific biosystem; |
Function : | 4 iron, 4 sulfur cluster binding; DNA N-glycosylase activity; DNA binding; DNA-(apurinic or apyrimidinic site) lyase activity; double-stranded DNA binding; endonuclease activity; hydrolase activity, acting on glycosyl bonds; lyase activity; metal ion binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
Nthl1-4519M | Recombinant Mouse Nthl1 Protein, Myc/DDK-tagged | +Inquiry |
NTHL1-107H | Recombinant Human NTHL1 Protein, His-tagged | +Inquiry |
NTHL1-3545C | Recombinant Chicken NTHL1 | +Inquiry |
NTHL1-2488H | Recombinant Human Nth Endonuclease III-Like 1 (E. coli), His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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