Recombinant Human NUC Protein, His tagged, Biotin Labeled, Animal free

Cat.No. : NUC-0020
Product Overview : Recombinant Human Nucleosome protein (Biotin) is a Human Full Length protein, in the 2 to 136 aa range, expressed in Escherichia coli. Human recombinant nucleosomes consisting of 147 bp DNA (PCR) and 2 molecules each of histones H2A, H2B, H3 and H4. Each histone protein has an N-terminal His-tag. Each H2B has a C-terminal Cys added as a biotinylation site.
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Species : Human
Source : E.coli
Tag : His
Protein Length : 2-36 aa
Conjugation/Label : Biotin
Description : Nucleosome is a fundamental unit of chromatin consisting of DNA wrapped around histone proteins. Alternate names include chromatin fibers and DNA-histone complexes. Each nucleosome contains an octamer of histones (two copies each of H2A H2B H3 and H4) with DNA coiled around it measuring about 11 nm in diameter. Nucleosomes are expressed in the nucleus of eukaryotic cells forming the basic structure of chromatin which further compacts to fit within the nucleus.
Form : pH: 7.5 Constituents: 20% Glycerol (glycerin, glycerine), 0.32% Tris HCl, 0.03% EDTA, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol
Molecular Mass : 113.8 kDa
AASequence : ARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
Purity : >95%, suitable for SDS-PAGE
Applications : SDS-PAGE
Storage : Appropriate short-term storage conditions: -80 centigrade Appropriate long-term storage conditions: -80 centigrade Storage information: Avoid freeze / thaw cycle, Store in the dark
Shipping : Dry Ice
Gene Name H2BC21 H2B clustered histone 21 [ Homo sapiens (human) ]
Official Symbol NUC
Synonyms H2BC21; H2B clustered histone 21; H2B; H2BE; H2BQ; GL105; H2B.1; H2BFQ; H2BGL105; H2B-GL105; HIST2H2BE; histone H2B type 2-E; H2B histone family, member Q; histone 2, H2be; histone H2B-GL105; histone H2B.q; histone cluster 2 H2B family member e; histone cluster 2, H2be
Gene ID 8349
mRNA Refseq NM_003528
Protein Refseq NP_003519
MIM 601831
UniProt ID Q16778

Not For Human Consumption!

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