Recombinant Human Nuclear Transport Factor 2-like Export Factor 2, His-tagged

• Cat.No.: NXT2-5546H
• Product Overview: Recombinant humanNXT2 protein, fused to His-tag at N-terminus, was expressed in E. coliand purified by using conventional chromatography techniques.

Specification

• Species: Human
• Tag: His
• Description: NXT2 isa member of NXT family proteins that are generally involved in exportingnuclear RNA in eukaryotic cells. This protein is regulatorof protein export for NES-containing proteins. Also, it associates with NXF1,NXF2, NXF3 and NXF5 and plays a role in mRNA nuclear export. NXT2 has acritical role in maintaining morphogenetic integrity of embryonic heart invertebrate species.
• Form: Liquid.In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 40% glycerol, 200mM NaCl.
• Molecular Weight: 25.3 kDa (221aa),confirmed by MALDI-TOF.
• Purity: > 95% by SDS-PAGE
• Concentration: 1 mg/ml(determined by Bradford assay)
• Sequences of aminoacids: MGSSHHHHHH SSGLVPRGSH MGSHMRKYRSHWSQGDREGY QRRSNYYEGP HTSHSSPADR TREEVVTPTL PEHTATRSQM ATSLDFKTYV DQACRAAEEFVNIYYETMDK RRRALTRLYL DKATLIWNGN AVSGLDALNN FFDTLPSSEF QVNMLDCQPV HEQATQSQTTVLVVTSGTVK FDGNKQHFFN QNFLLTAQST PNNTVWKIAS DCFRFQDWSS S
• Storage: Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• OfficialSymbol: NXT2
• Pathways: Exonjunction complex (EJC); Influenza A; RNA transport; Ribosome biogenesis ineukaryotes; mRNA surveillance pathway

Gene Information

• Gene Name: NXT2nuclear transport factor 2-like export factor 2 [ Homo sapiens ]
• Synonyms: NXT2; nucleartransport factor 2-like export factor 2; P15-2; OTTHUMP00000023840;OTTHUMP00000023841; OTTHUMP00000023842; OTTHUMP00000023843; NTF2-relatedexport protein 2; BM-025; DC9; Protein p15-2
• Gene ID: 55916
• mRNA Refseq: NM_018698
• Protein Refseq: NP_061168
• MIM: 300320
• UniProt ID: Q9NPJ8
• Chromosome Location: Xq22.3