Recombinant Human ODC1

• Cat.No.: ODC1-30519TH
• Product Overview: Recombinant full length Human Ornithine Decarboxylase with N terminal proprietary tag, 76.82kDa.

Specification

• Description: This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter.
• Protein length: 461 amino acids
• Molecular Weight: 76.820kDa inclusive of tags
• Source: Wheat germ
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MNNFGNEEFDCHFLDEGFTAKDILDQKINEVSSSDDKDAF YVADLGDILKKHLRWLKALPRVTPFYAVKCNDSKAIVKTL AATGAGFDCASKTEIQLVQSLGVPPERIIYANPCKQVSQI KYAANNGVQMMTFDSEVELMKVARAHPKAKLVLRIATDDS KAVCRLSVKFGATLRTSRLLLERAKELNIDVVGVSFHVGS GCTDPETFVQAISDARCVFDMGAEVGFSMYLLDIGGGFPG SEDVKLKFEEITGVINPALDKYFPSDSGVRIIAEPGRYYV ASAFTLAVNIIAKKIVLKEQTGSDDEDESSEQTFMYYVND GVYGSFNCILYDHAHVKPLLQKRPKPDEKYYSSSIWGPTC DGLDRIVERCDLPEMHVGDWMLFENMGAYTVAAASTFNGF QRPTIYYVMSGPAWQLMQQFQNPDFPPEVEEQDASTLPVS CAWESGMKRHRAACASASINV
• Sequence Similarities: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

Gene Information

• Gene Name: ODC1 ornithine decarboxylase 1 [ Homo sapiens ]
• Official Symbol: ODC1
• Synonyms: ODC1; ornithine decarboxylase 1; ornithine decarboxylase; ODC
• Gene ID: 4953
• mRNA Refseq: NM_002539
• Protein Refseq: NP_002530
• MIM: 165640
• Uniprot ID: P11926
• Chromosome Location: 2p25
• Pathway: Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Glutathione metabolism, organism-specific biosystem; Glutathione metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem
• Function: lyase activity; ornithine decarboxylase activity