Recombinant Human OGG1 Protein
Cat.No. : | OGG1-108H |
Product Overview : | Recombinant Human OGG1(Met1-Gly345), transcript variant 1a, was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. |
Source : | E. coli |
Species : | Human |
Form : | 20mM Tris-HCl, 100mM NaCl, 1mM DTT, 1mM EDTA, 50% Glycerol, pH 7.8. |
Molecular Mass : | 65.1 kDa |
Protein length : | Met1-Gly345 |
Endotoxin : | < 0.1 EU per µg protein as determined by LAL test |
Purity : | >95% as determined by SDS-PAGE and Coomassie blue staining |
Storage : | Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | OGG1 8-oxoguanine DNA glycosylase [ Homo sapiens ] |
Official Symbol : | OGG1 |
Synonyms : | OGG1; 8-oxoguanine DNA glycosylase; N-glycosylase/DNA lyase; 8 hydroxyguanine DNA glycosylase; HMMH; HOGG1; MUTM; OGG1 type 1d; OGG1 type 1e; OGG1 type 1g; OGG1 type 1h; OGH1; AP lyase; OGG1 type 1f; 8-hydroxyguanine DNA glycosylase; DNA-apurinic or apyrimidinic site lyase; |
Gene ID : | 4968 |
mRNA Refseq : | NM_002542 |
Protein Refseq : | NP_002533 |
MIM : | 601982 |
UniProt ID : | O15527 |
Products Types
◆ Recombinant Protein | ||
OGG1-1846H | Recombinant Human OGG1 Protein (1-345 aa), His-tagged | +Inquiry |
OGG1-6326M | Recombinant Mouse OGG1 Protein, His (Fc)-Avi-tagged | +Inquiry |
OGG1-238H | Recombinant Human OGG1 Protein (Met1-Gly345), C-His tagged, Animal-free, Carrier-free | +Inquiry |
OGG1-3823R | Recombinant Rat OGG1 Protein, His (Fc)-Avi-tagged | +Inquiry |
OGG1-2977R | Recombinant Rhesus Macaque OGG1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
OGG1-1246HCL | Recombinant Human OGG1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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