Recombinant Human ORC3L cell lysate

• Cat.No.: ORC3L-1259HCL

Specification

• Description: The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Studies of a similar gene in Drosophila suggested a possible role of this protein in neuronal proliferation and olfactory memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: ORC3 origin recognition complex, subunit 3 [ Homo sapiens(human) ]
• Official Symbol: ORC3L
• Synonyms: ORC3; LAT; ORC3L; LATHEO; origin recognition complex, subunit 3; origin recognition complex subunit 3; homolog of latheo, Drosophila; origin recognition complex subunit Latheo; origin recognition complex, subunit 3 honolog
• Gene ID: 23595
• mRNA Refseq: NM_001197259
• Protein Refseq: NP_001184188
• MIM: 604972
• UniProt ID: Q9UBD5
• Chromosome Location: 6q14.3-q16.1
• Pathway: Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Assembly of the pre-replicative complex
• Function: DNA replication origin binding; protein binding