Recombinant Human ORC4 Protein (1-436 aa), His-SUMO-tagged
Cat.No. : | ORC4-703H |
Product Overview : | Recombinant Human ORC4 Protein (1-436 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Research Area: Transcription. Protein Description: Full Length. |
- Specification
- Gene Information
- Related Products
Description : | Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3. |
Source : | E. coli |
Species : | Human |
Tag : | His-SUMO |
Form : | Tris-based buffer, 50% glycerol |
Molecular Mass : | 66.4 kDa |
Protein length : | 1-436 aa |
AA Sequence : | MSSRKSKSNSLIHTECLSQVQRILR ERFCRQSPHSNLFGVQVQYKHLSEL LKRTALHGESNSVLIIGPRGSGKTM LINHALKELMEIEEVSENVLQVHLN GLLQINDKIALKEITRQLNLENVVG DKVFGSFAENLSFLLEALKKGDRTS SCPVIFILDEFDLFAHHKNQTLLYN LFDISQSAQTPIAVIGLTCRLDILE LLEKRVKSRFSHRQIHLMNSFGFPQ YVKIFKEQLSLPAEFPDKVFAEKWN ENVQYLSEDRSVQEVLQKHFNISKN LRSLHMLLMLALNRVTASHPFMTAV DLMEASQLCSMDSKANIVHGLSVLE ICLIIAMKHLNDIYEEEPFNFQMVY NEFQKFVQRKAHSVYNFEKPVVMKA FEHLQQLELIKPMERTSGNSQREYQ LMKLLLDNTQIMNALQKYPNCPTDV RQWATSSLSWL |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA with concentration instruction is sent along with the products. |
Gene Name : | ORC4 origin recognition complex, subunit 4 [ Homo sapiens ] |
Official Symbol : | ORC4 |
Synonyms : | ORC4; HsORC4; Orc4p; ORC4L; ORC4P; FLJ46668; |
Gene ID : | 5000 |
mRNA Refseq : | NM_001190879 |
Protein Refseq : | NP_001177808 |
MIM : | 603056 |
UniProt ID : | O43929 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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