Cat.No. : |
OS9-6038H |
Product Overview : |
OS9 MS Standard C13 and N15-labeled recombinant protein (NP_001017958) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
Description : |
This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
73.82 kDa |
AA Sequence : |
MAAETLLSSL LGLLLLGLLL PASLTGGVGS LNLEELSEMR YGIEILPLPV MGGQSQSSDV VIVSSKYKQR YECRLPAGAI HFQREREEET PAYQGPGIPE LLSPMRDAPC LLKTKDWWTY EFCYGRHIQQ YHMEDSEIKG EVLYLGYYQS AFDWDDETAK ASKQHRLKRY HSQTYGNGSK CDLNGRPREA EVRFLCDEGA GISGDYIDRV DEPLSCSYVL TIRTPRLCPH PLLRPPPSAA PQAILCHPSL QPEEYMAYVQ RQADSKQYGD KIIEELQDLG PQVWSETKSG VAPQKMAGAS PTKDDSKDSD FWKMLNEPED QAPGGEEVPA EEQDPSPEAA DSASGAPNDF QNNVQVKVIR SPADLIRFIE ELKGGTKKGK PNIGQEQPVD DAAEVPQREP EKERGDPERQ REMEEEEDED EDEDEDEDER QLLGEFEKEL EGILLPSDRD RLRSETEKEL DPDGLKKESE RDRAMLALTS TLNKLIKRLE EKQSPELVKK HKKKRVVPKK PPPSPQPTEE DPEHRVRVRV TKLRLGGPNQ DLTVLEMKRE NPQLKQIEGL VKELLEREGL TAAGKIEIKI VRPWAEGTEE GARWLTDEDT RNLKEIFFNI LVPGAEEAQK ERQRQKELES NYRRVWGSPG GEGTGDLDEF DFTRTRPLEQ KLISEEDLAA NDILDYKDDD DKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
SDS-PAGE : |
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