Description : |
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors that play a key role in the maintenance of cholesterol balance in the body. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. This gene has been shown to be imprinted, with preferential expression from the maternal allele only in placenta. Transcript variants encoding different isoforms have been identified. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
90.6 kDa |
AA Sequence : |
MKEEAFLRRRFSLCPPSSTPQKVDP RKLTRNLLLSGDNELYPLSPGKDME PNGPSLPRDEGPPTPSSATKVPPAE YRLCNGSDKECVSPTARVTKKETLK AQKENYRQEKKRATRQLLSALTDPS VVIMADSLKGPKGESVGSITQPLPS SYLIFRAASESDGRCWLDALELALR CSSLLRLGTCKPGRDGEPGTSPDAS PSSLCGLPASATVHPDQDLFPLNGS SLENDAFSDKSERENPEESDTETQD HSRKTESGSDQSETPGAPVRRGTTY VEQVQEELGELGEASQVETVSEENK SLMWTLLKQLRPGMDLSRVVLPTFV LEPRSFLNKLSDYYYHADLLSRAAV EEDAYSRMKLVLRWYLSGFYKKPKG IKKPYNPILGETFRCCWFHPQTDSR TFYIAEQVSHHPPVSAFHVSNRKDG FCISGSITAKSRFYGNSLSALLDGK ATLTFLNRAEDYTLTMPYAHCKGIL YGTMTLELGGKVTIECAKNNFQAQL EFKLKPFFGGSTSINQISGKITSGE EVLASLSGHWDRDVFIKEEGSGSSA LFWTPSGEVRRQRLRQHTVPLEEQT ELESERLWQHVTRAISKGDQHRATQ EKFALEEAQRQRARERQESLMPWKP QLFHLDPITQEWHYRYEDHSPWDPL KDIAQFEQDGILRTLQQEAVARQTT FLGSPGPRHERSGPDQRLRKASDQP SGHSQATESSGSTPESCPELSDEEQ DGDFVPGGESPCPRCRKEARRLQAL HEAILSIREAQQELHRHLSAMLSST ARAAQAPTPGLLQSPRSWFLLCVFL ACQLFINHILKTRTRPLEQKLISEE DLAANDILDYKDDDDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |