Recombinant Human OSMR Protein, MYC/DDK-tagged

• Cat.No.: OSMR-454H
• Product Overview: Recombinant human OSMR protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Description: This gene encodes a member of the type I cytokine receptor family. The encoded protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in this gene have been associated with familial primary localized cutaneous amyloidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009].
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 40 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: oncostatin M receptor [ Homo sapiens ]
• Official Symbol: OSMR
• Synonyms: IL-31R-beta; IL-31RB; OSMRB; PLCA1
• Gene ID: 9180
• mRNA Refseq: NM_001168355.1
• Protein Refseq: NP_001161827.1
• MIM: 601743
• UniProt ID: Q99650